Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848292 | 0.89 | POLB (0.47) | ALDH1A1POLBSMN1; SMN2MAPK1HPGD | |
| SCHEMBL9186785 | 0.81 | CYP1A2 (0.71) | ALDH1A1POLBSMN1; SMN2MAPK1HPGD | |
| SCHEMBL9217493 | 0.74 | CYP1A2 (0.44) | ALDH1A1POLBSMN1; SMN2MAPK1HPGD | |
| SCHEMBL9215944 | 0.73 | HTR1A (0.49) | ALDH1A1SMN1; SMN2MAPK1HPGDHSD17B10 | |
| SCHEMBL5848920 | 0.73 | CYP2A6 (0.31) | — | |
| SCHEMBL6346878 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2MAPK1HPGD | |
| SCHEMBL5230385 | 0.72 | PDK1 (0.56) | ALDH1A1POLBSMN1; SMN2MAPK1HPGD | |
| SCHEMBL6799340 | 0.72 | CYP1A2 (0.65) | ALDH1A1POLBSMN1; SMN2MAPK1HPGD | |
| SCHEMBL5849619 | 0.72 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CYP2C9L3MBTL1LMNA | |
| SCHEMBL10804962 | 0.71 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MAPK1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105524-B2 | Pesticidal and parasiticidal di-and trifluorosubstituted alkene compounds | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20040254199-A1 | Pesticidal and parasiticidal di-and trifluorosubstituted alkene compounds | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | US | disclosed |
| EP-1436291-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | Aventis Pharma S.A. (FR) | 2004-07-14 | — | — | EP | disclosed |
| EP-1427287-A1 | PESTICIDAL AND PARASITICAL DI-AND TRIFLUOROSUBSTITUTED ALKENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003039258-A1 | PESTICIDAL AND PARASITICAL DI-AND TRIFLUOROSUBSTITUTED ALKENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003024967-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254199-A1 | Pesticidal and parasiticidal di-and trifluorosubstituted alkene compounds | DDT, ADRA1D, NR2E1 | ALDH1A1 415/4885POLB 4379/4885SMN1; SMN2 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.