Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217493 | 0.75 | CYP1A2 (0.44) | HTR1AHTR7HTR2ACYP1A2CYP2D6 | |
| SCHEMBL9211417 | 0.74 | PDK1 (0.54) | HTR1AHTR7HTR2ACYP1A2CYP2D6 | |
| SCHEMBL5847703 | 0.73 | ALDH1A1 (0.47) | HTR1AHTR7HTR2ACYP1A2CYP2D6 | |
| SCHEMBL10804962 | 0.72 | SMN1; SMN2 (0.53) | CYP1A2CYP2D6ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9745202 | 0.70 | HTR1A (0.55) | HTR1AHTR7HTR2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9216533 | 0.68 | LATS1 (0.34) | CYP2C9 | |
| SCHEMBL9214919 | 0.68 | USP2 (0.47) | CYP1A2CYP2D6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9217936 | 0.68 | CHRNB2 (0.41) | — | |
| SCHEMBL9213491 | 0.67 | ALOX5 (0.36) | HTR1AHTR7HTR2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9213780 | 0.67 | MAPT (0.62) | ALDH1A1HSD17B10CYP2C9HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |