Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944419 | 0.96 | CA2 (0.44) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL2466680 | 0.82 | CA2 (0.44) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL6907770 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL6913062 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL6912839 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL6913341 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL9486268 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| Zinc Ion SCHEMBL6909025 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL6914451 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 | |
| SCHEMBL6912831 | 0.79 | LMNA (0.42) | CA2CA12CA9PLCG1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220363894-A1 | RESIN COMPOSITION AND ELECTRONIC/ELECTRIC EQUIPMENT COMPONENT | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2022-11-17 | — | — | US | disclosed |
| EP-2617772-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED ARTICLE OF SAME | MITSUBISHI ENG PLASTICS CORP (JP) | 2020-02-12 | — | — | EP | disclosed |
| US-9522519-B2 | Polycarbonate resin laminate | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-12-20 | — | — | US | disclosed |
| EP-2740598-B1 | POLYCARBONATE RESIN LAMINATE | MITSUBISHI CHEM CORP (JP) | 2016-05-25 | — | — | EP | disclosed |
| EP-2740598-A1 | POLYCARBONATE RESIN LAMINATE | Mitsubishi Chemical Corporation (JP) | 2014-06-11 | — | — | EP | disclosed |
| US-20140147651-A1 | POLYCARBONATE RESIN LAMINATE | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2014-05-29 | — | — | US | disclosed |
| EP-2617772-A1 | POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED ARTICLE OF SAME | Mitsubishi Engineering-Plastics Corporation (JP) | 2013-07-24 | — | — | EP | disclosed |
| EP-1832613-B9 | GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER | KANEKA CORP (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-1832613-B1 | GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER | KANEKA CORP (JP) | 2012-02-15 | — | — | EP | disclosed |
| EP-1605320-B1 | Transfer medium carrying member, intermediate transfer member and image forming apparatus using the same | CANON KK (JP) | 2009-04-22 | — | — | EP | disclosed |
| US-20080242797-A1 | Organopolysiloxane-Containing Graft Copolymer Composition | KANEKA CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080085975-A1 | Graft Copolymer, Method For Producing The Same And Resin Composition Containing The Graft Copolymer | KANEKA CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |
| EP-1832613-A1 | GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER | Kaneka Corporation (JP) | 2007-09-12 | — | — | EP | disclosed |
| US-20070178312-A1 | TRANSFER MEDIUM CARRYING MEMBER, INTERMEDIATE TRANSFER MEMBER AND IMAGE FORMING APPARATUS USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1731568-A1 | ORGANOPOLYSILOXANE-CONTAINING GRAFT COPOLYMER COMPOSITION | Kaneka Corporation (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-1605320-A2 | Transfer medium carrying member, intermediate transfer member and image forming apparatus using the same | CANON KABUSHIKI KAISHA (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20050271879-A1 | Transfer medium carrying member, intermediate transfer member and image forming apparatus using the same | CANON KABUSHIKI KAISHA (JP) | 2005-12-08 | — | — | US | disclosed |
| US-6369141-B1 | AROMATIC POLYPHOSPHATE, POLYFLUOROETHYLENE, AND SHELL-CORE POLYMER WITH ALKYL (METH)ACRYLATE EXTERIOR LAYER; MECHANICAL PROPERTIES, HEAT RESISTANCE, STABILITY; ELECTRONICS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2002-04-09 | — | — | US | disclosed |
| US-6342550-B1 | ORGANIC SULFONIC ACID METAL SALT,FLUORINATED POLYOLEFIN, DIENE MULTI-LAYERED POLYMER, PHOSPHORUS FREE; IMPACT RESISTANCE, HEAT RESISTANCE, MOLDABILITY, CHEMICAL REESISTANCE | MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) | 2002-01-29 | — | — | US | disclosed |