SCHEMBL58582

SCHEMBL58582

c1ccc(-c2cccc(-c3conn3)c2-c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMARCA2 P51531 2/20 0.33
SMARCA4 P51532 2/20 0.33
PBRM1 Q86U86 2/20 0.33
TDO2 P48775 1/20 0.33
ENPP1 P22413 2/20 0.33
ENPP3 O14638 1/20 0.33
HNF4A P41235 1/20 0.33
BRD4 O60885 1/20 0.32
NR1I2 O75469 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
NOTUM Q6P988 1/20 0.32
ASIC3 Q9UHC3 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ALDH1A1 P00352 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8998624 0.89 RAB9A (0.39) RAB9AMEN1KMT2ASMARCA2SMARCA4
SCHEMBL6135309 0.85 GPR55 (0.39) RAB9ASMARCA2SMARCA4PBRM1TDO2
SCHEMBL2200428 0.84 GPR55 (0.38) RAB9ASMARCA2SMARCA4PBRM1TDO2
SCHEMBL6853266 0.79 PTPN5 (0.32) MEN1KMT2AENPP1ENPP3
SCHEMBL6723504 0.79 MEN1 (0.33) MEN1KMT2A
SCHEMBL673264 0.75 BCAT2 (0.46) RAB9AMEN1KMT2ASMARCA2SMARCA4
SCHEMBL192418 0.74 ALDH1A1 (0.50) ENPP1HNF4AHDAC4HDAC2HDAC8
SCHEMBL3181328 0.72 SMARCA2 (0.37) RAB9AMEN1KMT2ASMARCA2SMARCA4
SCHEMBL11287400 0.72 NFE2L2 (0.37) MEN1KMT2ABRD4MAOB
Phosphine SCHEMBL10935474 0.72 ALDH1A1 (0.48) ENPP1HNF4AHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866110-B1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MFG CO (JP) 2004-10-20 EP claimed
US-8129903-B2 Organic electroluminescent display device KABUSHIKI KAISHA TOSHIBA (JP) 2012-03-06 US disclosed
US-20090243484-A1 ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2009-10-01 US disclosed
US-7234853-B2 Textile product with illuminated fibers manufacturing process LUMINEX S.P.A. (IT) 2007-06-26 US disclosed
EP-1307687-B1 TEXTILE PRODUCT WITH ILLUMINATED FIBRES, ARTICLE MADE THEREFROM AND PRODUCTION METHOD OF THE SAME LUMINEX S P A (IT) 2006-03-08 EP disclosed
EP-0866110-B1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MFG CO (JP) 2004-10-20 EP disclosed
EP-1307687-A1 TEXTILE PRODUCT WITH ILLUMINATED FIBRES, ARTICLE MADE THEREFROM AND PRODUCTION METHOD OF THE SAME Luminex S.p.A. (IT) 2003-05-07 EP disclosed
WO-2002012785-A1 TEXTILE PRODUCT WITH ILLUMINATED FIBRES, ARTICLE MADE THEREFROM AND PRODUCTION METHOD OF THE SAME LUMINEX S.P.A. (IT) 2002-02-14 WO disclosed
US-20010033944-A1 LIGHT-EMITTING MATERIAL FOR ORGANO-ELECTROLUMINESCENCE DEVICE AND FOR ORGANIC ELECTROLUMINESCENCE DEVICE WHICH THE MATERIAL IS APPLIED TOYO INK MANUFACTURING CO., LTD. (JP) 2001-10-25 US disclosed
US-6280859-B1 AROMATIC ELECTROLUMINESCENT MATERIAL OR NONSUBSTITUTED HETEROAROMATIC GROUP OR DIVALENT GROUP TOYO INK MANUFACTURING CO., LTD. (JP) 2001-08-28 US disclosed
EP-0934992-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1999-08-11 EP disclosed
EP-0866110-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010033944-A1 LIGHT-EMITTING MATERIAL FOR ORGANO-ELECTROLUMINESCENCE DEVICE AND FOR ORGANIC ELECTROLUMINESCENCE DEVICE WHICH THE MATERIAL IS APPLIED L1CAM, ELP1, CRY1 RAB9A 2194/4885MEN1 254/4885KMT2A 2420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.