Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859208 | 0.89 | PDE4B (0.43) | DHODHLMNAALDH1A1HPGDKDM4E | |
| SCHEMBL5862164 | 0.88 | GPR35 (0.44) | GPR35GSK3BPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL5859069 | 0.84 | NPC1 (0.46) | LMNAALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL6661310 | 0.84 | ALDH1A1 (0.47) | LMNAALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL5859860 | 0.83 | IKBKB (0.37) | DHODHKDM4EPOLB | |
| SCHEMBL5862147 | 0.82 | KDM4E (0.42) | GPR35DHODHLMNAALDH1A1HPGD | |
| SCHEMBL5859907 | 0.82 | RAB9A (0.49) | ALDH1A1HPGDKDM4E | |
| SCHEMBL5862118 | 0.80 | GPR35 (0.46) | GPR35DHODHALDH1A1KDM4EPOLB | |
| SCHEMBL5859855 | 0.78 | NPC1 (0.51) | DHODHGSK3BLMNAALDH1A1HPGD | |
| SCHEMBL5862046 | 0.75 | NPC1 (0.50) | GSK3BLMNAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |