Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 11/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.34 |
| ▸ | PRKACA | P17612 | 5/20 | 0.33 |
| ▸ | GSK3B | P49841 | 5/20 | 0.33 |
| ▸ | PRKG1 | Q13976 | 5/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | GSK3A | P49840 | 4/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.33 |
| ▸ | PRKX | P51817 | 4/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | AKT2 | P31751 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859860 | 0.82 | IKBKB (0.37) | AURKB | |
| SCHEMBL5859140 | 0.82 | CNR1 (0.45) | ROCK1ROCK2CNR2 | |
| SCHEMBL5859281 | 0.81 | CYP3A4 (0.48) | SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL6655451 | 0.80 | CNR1 (0.48) | HTTROCK1ROCK2ALDH1A1CNR2 | |
| SCHEMBL5859873 | 0.79 | CNR1 (0.50) | SMN1; SMN2HTTROCK1ROCK2ALDH1A1 | |
| SCHEMBL5860337 | 0.79 | APOB (0.44) | — | |
| SCHEMBL5862246 | 0.76 | CYP2C9 (0.41) | HTTALDH1A1CYP2C9 | |
| SCHEMBL5859258 | 0.74 | ALDH1A1 (0.40) | SMN1; SMN2HTTMAPK1ALDH1A1 | |
| SCHEMBL5859051 | 0.74 | CYP46A1 (0.39) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PTK2 | |
| SCHEMBL5859208 | 0.73 | PDE4B (0.43) | HTTALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-20040039061-A1 | Substituted benzoic acid derivatives exhibiting nf-k b inhibiting activity | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039061-A1 | Substituted benzoic acid derivatives exhibiting nf-k b inhibiting activity | NFKBIA, NFKB2, IKBKB | TAS1R3 4332/4885TAS1R1 4038/4885TAS1R2 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.