Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655451 | 0.99 | CNR1 (0.48) | CNR1CNR2RAB9ANPC1L3MBTL1 | |
| SCHEMBL5859140 | 0.95 | CNR1 (0.45) | CNR1CNR2ROCK2ROCK1 | |
| SCHEMBL5859860 | 0.81 | IKBKB (0.37) | KDM4E | |
| SCHEMBL5862246 | 0.80 | CYP2C9 (0.41) | RAB9AALDH1A1HTTMEN1KMT2A | |
| SCHEMBL5859281 | 0.79 | CYP3A4 (0.48) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL5859286 | 0.79 | TAS1R3 (0.38) | CNR2ALDH1A1HTTROCK2ROCK1 | |
| SCHEMBL5860337 | 0.77 | APOB (0.44) | — | |
| SCHEMBL5859258 | 0.75 | ALDH1A1 (0.40) | RAB9ANPC1L3MBTL1ALDH1A1HTT | |
| SCHEMBL5859099 | 0.74 | CNR2 (0.42) | CNR1CNR2RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL5862115 | 0.73 | ROCK2 (0.41) | CNR1CNR2RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |