Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376288 | 0.73 | CRHR1 (0.33) | — | |
| SCHEMBL7058487 | 0.72 | GABRA1 (0.34) | — | |
| SCHEMBL299309 | 0.70 | GABRA1 (0.47) | — | |
| SCHEMBL14882190 | 0.66 | — | — | |
| SCHEMBL3547696 | 0.65 | CYP3A4 (0.45) | — | |
| SCHEMBL2788522 | 0.64 | GABRA1 (0.41) | — | |
| SCHEMBL2536793 | 0.64 | GABRA1 (0.36) | — | |
| SCHEMBL9442884 | 0.63 | GABRA1 (0.37) | — | |
| SCHEMBL13281358 | 0.63 | GABRA1 (0.38) | — | |
| SCHEMBL9279818 | 0.62 | GABRA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507783-B1 | HYDROXY DIPHOSPHINES AND THEIR USE IN CATALYSIS | DEGUSSA (DE) | 2006-12-27 | — | — | EP | claimed |
| US-7081533-B2 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2006-07-25 | — | — | US | claimed |
| US-20060089469-A1 | Hydroxy diphosphines and their use in catalysis | DEGUSSA AG (DE) | 2006-04-27 | — | — | US | claimed |
| EP-1507783-A1 | HYDROXY DIPHOSPHINES AND THEIR USE IN CATALYSIS | Degussa AG (DE) | 2005-02-23 | — | — | EP | claimed |
| EP-1311517-B1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | DEGUSSA (DE) | 2004-07-14 | — | — | EP | claimed |
| US-20040019205-A1 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2004-01-29 | — | — | US | claimed |
| EP-1201673-B1 | Bidentate organophosphorous ligands and their use in catalysis | DEGUSSA (DE) | 2004-01-14 | — | — | EP | claimed |
| WO-2003099832-A1 | HYDROXY DIPHOSPHINES AND THEIR USE IN CATALYSIS | DEGUSSA AG (DE) | 2003-12-04 | — | — | WO | claimed |
| US-6573389-B1 | As catalysts for asymmetric reaction or polymerization | DEGUSSA AG (DE) | 2003-06-03 | — | — | US | claimed |
| EP-1175426-B1 | BIDENTATE ORGANOPHOSPHOROUS LIGANDS AND THEIR USE | DEGUSSA (DE) | 2003-05-28 | — | — | EP | claimed |
| EP-1311517-A1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | Degussa AG (DE) | 2003-05-21 | — | — | EP | claimed |
| JP-2002543086-A | — | — | 2002-12-17 | — | — | JP | claimed |
| US-6476246-B2 | UNSYMMETRICAL BICYCLOALIPHATIC CHIRAL DIPHOSPHINES AND PHOSPHINE PHOSPHINITES, COMPLEXES OF THESE COMPOUNDS WITH METALS OF GROUPS VIIB, VIIIB AND IB AS HYDROGENATION CATALYSTS | DEGUSSA AG (DE) | 2002-11-05 | — | — | US | claimed |
| US-20020095049-A1 | Unsymmetrical bicycloaliphatic chiral diphosphines and phosphine phosphinites, complexes of these compounds with metals of groups VIIb, VIIIb and Ib as hydrogenation catalysts | DEGUSSA AG (DE) | 2002-07-18 | — | — | US | claimed |
| EP-1201673-A1 | Bidentate organophosphorous ligands and their use in catalysis | Degussa Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | claimed |
| WO-2002014330-A1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | DEGUSSA AG (DE) | 2002-02-21 | — | — | WO | claimed |
| EP-1175426-A1 | BIDENTATE ORGANOPHOSPHOROUS LIGANDS AND THEIR USE | Degussa AG (DE) | 2002-01-30 | — | — | EP | claimed |
| WO-2000064914-A1 | BIDENTATE ORGANOPHOSPHOROUS LIGANDS AND THEIR USE | DEGUSSA AG (DE) | 2000-11-02 | — | — | WO | claimed |
| US-7081533-B2 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2006-07-25 | — | — | US | disclosed |
| WO-2000064914-A1 | BIDENTATE ORGANOPHOSPHOROUS LIGANDS AND THEIR USE | DEGUSSA AG (DE) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089469-A1 | Hydroxy diphosphines and their use in catalysis | GNPAT, DCPS, HDHD5 | CHKA 840/4885 |
| US-20020095049-A1 | Unsymmetrical bicycloaliphatic chiral diphosphines and phosphine phosphinites, complexes of these compounds with metals of groups VIIb, VIIIb and Ib as hydrogenation catalysts | INPP5B, PI4K2B, PIP4K2B | CHKA 1170/4885 |
| US-20040019205-A1 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | GNPAT, PNKP, PHOSPHO1 | CHKA 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.