SCHEMBL5859593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5859589	0.89	KIF11 (0.43)	KIF11GPR84FFAR1KMT2AMEN1
	SCHEMBL7541639	0.81	KIF11 (0.40)	KIF11NPC1RAB9A
	SCHEMBL7147418	0.79	CNR1 (0.40)	CNR1CNR2
	SCHEMBL7144172	0.79	CNR1 (0.40)	CNR1CNR2
	SCHEMBL15212062	0.77	KIF11 (0.40)	KIF11CNR1CNR2NPC1RAB9A
	SCHEMBL6855010	0.77	L3MBTL1 (0.39)	KIF11CNR1CNR2KMT2ANPC1
	SCHEMBL15212175	0.75	NFE2L2 (0.39)	KIF11CNR1CNR2KMT2ANPC1
	SCHEMBL5133757	0.74	NFE2L2 (0.40)	KMT2ANPC1RAB9AMEN1
	SCHEMBL8457737	0.73	KMT2A (0.42)	USP2KMT2ANPC1RAB9AMEN1
	SCHEMBL7144402	0.72	MEN1 (0.42)	KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.