Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LIPA | P38571 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900059 | 1.00 | GLA (0.44) | GLAHSD11B1EPHX1NPC1LIPA | |
| SCHEMBL5728882 | 1.00 | GLA (0.44) | GLAHSD11B1EPHX1NPC1LIPA | |
| SCHEMBL27549896 | 0.80 | GLA (0.47) | GLAHSD11B1EPHX1NPC1LIPA | |
| SCHEMBL1506461 | 0.79 | CHRNB2 (0.36) | MAPT | |
| SCHEMBL1060400 | 0.79 | CHRNB2 (0.36) | MAPT | |
| SCHEMBL890380 | 0.79 | CHRNB2 (0.36) | MAPT | |
| SCHEMBL4279 | 0.79 | — | — | |
| SCHEMBL503482 | 0.78 | GLA (0.50) | GLAHSD11B1EPHX1NPC1LIPA | |
| SCHEMBL1835036 | 0.78 | GLA (0.46) | GLAHSD11B1EPHX1NPC1LIPA | |
| SCHEMBL1835961 | 0.78 | GLA (0.50) | GLAHSD11B1EPHX1NPC1LIPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4317128-B1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2025-07-23 | — | — | EP | disclosed |
| US-12358864-B2 | Trisamide compounds and compositions comprising the same | MILLIKEN & COMPANY (US) | 2025-07-15 | — | — | US | disclosed |
| CN-117756661-A | Triamide compound and composition comprising same | 美利肯公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4317128-A2 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | Milliken & Company (US) | 2024-02-07 | — | — | EP | disclosed |
| EP-4073029-B1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2024-01-31 | — | — | EP | disclosed |
| CN-115066413-B | Triamide compound and composition comprising same | 美利肯公司 | 2024-01-09 | — | — | CN | disclosed |
| US-20230331660-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY | 2023-10-19 | — | — | US | disclosed |
| US-11724983-B2 | Trisamide compounds and compositions comprising the same | MILLIKEN & COMPANY (US) | 2023-08-15 | — | — | US | disclosed |
| EP-4073029-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | Milliken & Company (US) | 2022-10-19 | — | — | EP | disclosed |
| CN-109071458-B | Triamide compounds and compositions comprising the same | 美利肯公司 | 2021-12-10 | — | — | CN | disclosed |
| EP-3426639-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | Milliken & Company (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2017-09-14 | — | — | US | disclosed |
| WO-2017156099-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| US-7074790-B2 | 5-ethylimidarotriazones | BAYER HEALTHCARE AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20060040942-A1 | 5-ethylimidarotriazones | BAYER HEALTHCARE AG (DE) | 2006-02-23 | — | — | US | disclosed |
| US-20050272732-A1 | 5-ethyl-imidazo (5,1-F) (1,2,4,) triazin-4 (3h)-ones as phosphodiesterase inhibitors | BAYER HEALTHCARE AG (DE) | 2005-12-08 | — | — | US | disclosed |
| EP-1506198-A1 | 5-ETHYLIMIDAROTRIAZONES | Bayer HealthCare AG (DE) | 2005-02-16 | — | — | EP | disclosed |
| EP-1504006-A1 | 5-ETHYL-IMIDAZO[5,1-F][1,2,4]TRIAZIN-4(3H)-ONES AS PHOSPHODIESTERASE INHIBITORS | Bayer Aktiengesellschaft (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097645-A1 | 5-ETHYLIMIDAROTRIAZONES | BAYER HEALTHCARE AG (DE) | 2003-11-27 | — | — | WO | disclosed |
| WO-2003093270-A1 | 5-ETHYL-IMIDAZO (5,1-F) (1,2,4,) TRIAZIN-4 (3H) -ONES AS PHOSPHODIESTERASE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040942-A1 | 5-ethylimidarotriazones | IL5, EPX, NFATC1 | GLA 3180/4885HSD11B1 2329/4885EPHX1 625/4885 |
| US-11724983-B2 | Trisamide compounds and compositions comprising the same | PTAR1, TIPRL, TCOF1 | GLA 612/4885HSD11B1 3105/4885EPHX1 3394/4885 |
| US-20230331660-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | PTAR1, TIPRL, TCOF1 | GLA 612/4885HSD11B1 3105/4885EPHX1 3394/4885 |
| US-12358864-B2 | Trisamide compounds and compositions comprising the same | PTAR1, TIPRL, TCOF1 | GLA 612/4885HSD11B1 3105/4885EPHX1 3394/4885 |
| US-20050272732-A1 | 5-ethyl-imidazo (5,1-F) (1,2,4,) triazin-4 (3h)-ones as phosphodiesterase inhibitors | PDE3A, PDE5A, PDE3B | GLA 1211/4885HSD11B1 614/4885EPHX1 196/4885 |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | TELO2, TERT, H1-2 | GLA 2538/4885HSD11B1 4237/4885EPHX1 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.