Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862734 | 0.81 | ALDH1A1 (0.46) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL5860161 | 0.70 | POLB (0.49) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL5860416 | 0.70 | RECQL (0.47) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL7787353 | 0.68 | ALDH1A1 (0.44) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL11141195 | 0.68 | MAPT (0.45) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL11622734 | 0.68 | KMT2A (0.50) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL32691849 | 0.67 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MAPTMAPK1CYP1A2 | |
| SCHEMBL11529772 | 0.67 | KMT2A (0.58) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL11627166 | 0.67 | CYP1A2 (0.75) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL1053453 | 0.66 | KMT2A (0.60) | KMT2AL3MBTL1RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169203-A1 | Ion channel modulating agents | NEUROSEARCH A/S (DK) | 2002-11-14 | — | — | US | claimed |
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |
| US-20160318854-A1 | Thioamides and Amides for Controlling Animal Pests | BASF SE (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160318854-A1 | Thioamides and Amides for Controlling Animal Pests | BASF SE (DE) | 2016-11-03 | — | — | US | disclosed |
| US-7012146-B2 | Ion channel modulating agents | POSEIDON PHARMACEUTICALS A/S (DK) | 2006-03-14 | — | — | US | disclosed |
| US-20020169203-A1 | Ion channel modulating agents | NEUROSEARCH A/S (DK) | 2002-11-14 | — | — | US | disclosed |
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318854-A1 | Thioamides and Amides for Controlling Animal Pests | TST, TMT1A, ACHE | KMT2A 171/4885L3MBTL1 118/4885RAB9A 1606/4885 |
| US-20020169203-A1 | Ion channel modulating agents | KCNN3, KCNN1, KCNN2 | KMT2A 1783/4885L3MBTL1 4454/4885RAB9A 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.