Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860476 | 1.00 | ADAMTS4 (0.51) | ADAMTS4TDP1TSHRLMNAHPGD | |
| SCHEMBL5861572 | 0.81 | ALDH1A1 (0.50) | TDP1TSHRLMNAHPGDGAA | |
| SCHEMBL2705958 | 0.81 | ALDH1A1 (0.50) | TDP1TSHRLMNAHPGDGAA | |
| SCHEMBL4124188 | 0.81 | ALDH1A1 (0.50) | TDP1TSHRLMNAHPGDGAA | |
| SCHEMBL28242825 | 0.80 | ALDH1A1 (0.47) | TDP1TSHRLMNAGAAALDH1A1 | |
| SCHEMBL939400 | 0.78 | LMNA (0.45) | TDP1TSHRLMNAHPGDGAA | |
| SCHEMBL16569135 | 0.78 | LMNA (0.45) | TDP1TSHRLMNAHPGDGAA | |
| SCHEMBL18553327 | 0.77 | POLB (0.49) | ADAMTS4LMNAGAAALDH1A1L3MBTL1 | |
| SCHEMBL30919964 | 0.77 | POLB (0.49) | ADAMTS4LMNAGAAALDH1A1L3MBTL1 | |
| SCHEMBL30920005 | 0.77 | POLB (0.49) | ADAMTS4LMNAGAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7145030-B2 | Production method for optically active N-aryl-β-amino acid compounds | AJINOMOTO CO., INC. (JP) | 2006-12-05 | — | — | US | disclosed |
| US-20040267043-A1 | Production method for optically active N-aryl-beta-amino acid compounds | AJINOMOTO CO., INC. (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-1471050-A1 | Production method for optically active N-aryl-beta-amino acid compounds | Ajinomoto Co., Inc. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267043-A1 | Production method for optically active N-aryl-beta-amino acid compounds | AADAT, AADAC, DDC | ADAMTS4 4509/4885TDP1 4634/4885TSHR 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.