Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454750 | 0.85 | EPHX2 (1.00) | EPHX2SIGMAR1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5049577 | 0.85 | EPHX2 (1.00) | EPHX2SIGMAR1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24011366 | 0.82 | SMN1; SMN2 (0.76) | EPHX2SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL652791 | 0.81 | LMNA (0.79) | EPHX2SIGMAR1ALDH1A1HPGDPOLB | |
| SCHEMBL3638096 | 0.81 | SIGMAR1 (0.58) | EPHX2SIGMAR1ALDH1A1POLBLMNA | |
| SCHEMBL16825757 | 0.81 | SIGMAR1 (0.58) | EPHX2SIGMAR1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4693545 | 0.80 | EPHX2 (0.71) | EPHX2SIGMAR1ALDH1A1LMNAMEN1 | |
| SCHEMBL21624779 | 0.80 | LMNA (0.55) | EPHX2SMN1; SMN2ALDH1A1POLBLMNA | |
| Hydrochloric Acid SCHEMBL6473105 | 0.79 | LMNA (0.77) | EPHX2SIGMAR1ALDH1A1HPGDPOLB | |
| SCHEMBL18396293 | 0.79 | HPGDS (0.62) | SMN1; SMN2HPGDNPC1RAB9AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041667-B1 | CCR5 modulators | PFIZER, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-20050014757-A1 | Azacyclic compounds | ANDERSSON CARL-MAGNUS A (DK) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014757-A1 | Azacyclic compounds | HTR6, TPMT, HNMT | EPHX2 1905/4885SIGMAR1 295/4885HTT 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.