Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865653 | 0.88 | ALDH1A1 (0.48) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL5865624 | 0.88 | VCAM1 (0.66) | TSHRMAPK1CYP3A4ATML3MBTL1 | |
| SCHEMBL5865249 | 0.85 | TSHR (0.50) | TSHRMAPK1CYP3A4ATML3MBTL1 | |
| SCHEMBL18547069 | 0.84 | VCAM1 (0.65) | TSHRMAPK1CYP3A4ATMALDH1A1 | |
| SCHEMBL5865568 | 0.82 | GPR35 (0.51) | TSHRMAPK1CYP3A4ATML3MBTL1 | |
| SCHEMBL3544563 | 0.82 | TSHR (0.58) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL31590506 | 0.82 | TSHR (0.58) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL360051 | 0.78 | CASP6 (0.70) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11549591 | 0.77 | CASP6 (0.68) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL340544 | 0.77 | MAPT (0.58) | TSHRMAPK1CYP3A4ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091248-B2 | Treatment of adrenocortical hypersecretion and tumor growth | BRANDT INGVAR | 2006-08-15 | — | — | US | disclosed |
| US-20040242705-A1 | Novel treatment of adrenocortical hypersecretion and tumour growth | BRANDT INGVAR (SE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242705-A1 | Novel treatment of adrenocortical hypersecretion and tumour growth | NR3C2, NR5A1, NR3C1 | TSHR 118/4885MAPK1 2454/4885CYP3A4 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.