Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 14/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5463380 | 0.99 | SIGMAR1 (0.43) | SIGMAR1CCR5KMT2AHTR7HTR2A | |
| SCHEMBL5467769 | 0.94 | CCR5 (0.42) | CCR5KMT2APRCP | |
| SCHEMBL5452648 | 0.94 | CCR5 (0.42) | CCR5KMT2APRCP | |
| SCHEMBL5867337 | 0.92 | KMT2A (0.41) | CCR5KMT2AHTR7HTR1APRCP | |
| Hydrochloric Acid SCHEMBL5448681 | 0.91 | KMT2A (0.41) | CCR5KMT2AHTR7HTR1APRCP | |
| SCHEMBL5868117 | 0.87 | HTR7 (0.42) | CCR5KMT2AHTR7HTR1APRCP | |
| SCHEMBL6715399 | 0.86 | PRCP (0.40) | CCR5KMT2APRCP | |
| Hydrochloric Acid SCHEMBL5459369 | 0.86 | HTR7 (0.41) | CCR5KMT2AHTR7HTR1APRCP | |
| SCHEMBL5458123 | 0.84 | KMT2A (0.44) | CCR5KMT2AHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL5458549 | 0.83 | KMT2A (0.43) | CCR5KMT2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153868-B2 | N-(3-(4-substituted-1-piperidinyl)-1-phenylpropyl) substituted sulfonamides as NK-3 receptor antagonists | MERCK SHARP & DOHME LTD. | 2006-12-26 | — | — | US | claimed |