Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 15/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452648 | 0.90 | CCR5 (0.42) | PRCPCCR5KMT2A | |
| SCHEMBL5467769 | 0.90 | CCR5 (0.42) | PRCPCCR5KMT2A | |
| SCHEMBL5867337 | 0.86 | KMT2A (0.41) | PRCPCCR5KMT2A | |
| SCHEMBL5867355 | 0.86 | SIGMAR1 (0.43) | PRCPCCR5KMT2A | |
| Hydrochloric Acid SCHEMBL5463380 | 0.86 | SIGMAR1 (0.43) | PRCPCCR5KMT2A | |
| Hydrochloric Acid SCHEMBL5448681 | 0.86 | KMT2A (0.41) | PRCPCCR5KMT2A | |
| SCHEMBL5868117 | 0.85 | HTR7 (0.42) | PRCPCCR5L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL5459369 | 0.84 | HTR7 (0.41) | PRCPCCR5L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL5867442 | 0.84 | TP53 (0.43) | PRCPCCR5KMT2A | |
| SCHEMBL5458123 | 0.80 | KMT2A (0.44) | CCR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002504-A1 | N-(3-(4-substituted-1-piperidinyl)-1-phenylpropyl) substituted sulfonamides as NK-3 receptor antagonists | MERCK SHARP & DOHME LTD. (GB) | 2004-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002504-A1 | N-(3-(4-substituted-1-piperidinyl)-1-phenylpropyl) substituted sulfonamides as NK-3 receptor antagonists | KCNH3, KCNH2, KCNK3 | PRCP 2192/4885CCR5 710/4885ATM 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.