Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16352314 | 0.76 | LMNA (0.56) | MAOBMAOAHSD11B1LMNASMN1; SMN2 | |
| SCHEMBL8766728 | 0.76 | LMNA (0.56) | MAOBMAOAHSD11B1LMNASMN1; SMN2 | |
| SCHEMBL28263951 | 0.76 | ALDH1A1 (0.57) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL12040557 | 0.76 | LMNA (0.57) | MAOBMAOAHSD11B1BACE1CNR2 | |
| SCHEMBL9418910 | 0.76 | MEN1 (0.49) | MAOBLMNASMN1; SMN2P2RX7MEN1 | |
| SCHEMBL9418932 | 0.76 | LMNA (0.34) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1332710 | 0.76 | CXCR3 (0.39) | LMNASMN1; SMN2EPHX2SIGMAR1MEN1 | |
| SCHEMBL4172174 | 0.75 | GRIN2D (0.47) | MAOBMAOAHSD11B1P2RX7 | |
| SCHEMBL8766773 | 0.74 | HSD11B1 (0.56) | MAOBMAOAHSD11B1BACE1CNR2 | |
| SCHEMBL11781557 | 0.74 | MAOB (0.46) | MAOBMAOAHSD11B1BACE1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109259-B2 | Piperazinone derivatives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-09-19 | — | — | US | disclosed |
| US-7049386-B2 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. (US) | 2006-05-23 | — | — | US | disclosed |
| EP-1133490-B1 | PIPERAZINONE DERIVATIVES | CIBA SC HOLDING AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| EP-1309639-A4 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INT INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6803441-B2 | INCORPORATING THERMOSETTING MONOMER HAS A CAGE COMPOUND OR ARYL CORE STRUCTURE, PLURALITY OF ARMS THAT ARE COVALENTLY BOUND TO THE CAGE COMPOUND OR CORE STRUCTURE INTO A POLYMER TO FORM THE LOW DIELECTRIC CONSTANT POLYMER | HONEYWELL INTERNATIONAL INC. | 2004-10-12 | — | — | US | disclosed |
| US-20040192870-A1 | Compositions and methods for thermosetting molecules in organic compositions | LAU KREISLER S (US) | 2004-09-30 | — | — | US | disclosed |
| WO-2004000909-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| US-6596461-B1 | Useful for stabilizing an organic material against degradation induced by light, heat or oxidation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |
| US-20030096938-A1 | Compositions and methods for thermosetting molecules in organic compositions | LAU KREISLER (US) | 2003-05-22 | — | — | US | disclosed |
| EP-1309639-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | Honeywell International, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| US-6046304-A | MIXTURE OF SPECIFIC BLOCK OLIGOMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION WITH TRIAZINE AND 2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS; USE AS LIGHT STABILIZERS, HEAT STABILIZERS AND OXIDATION STABILIZERS SUCH AS FOR SYNTHETIC POLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-04-04 | — | — | US | disclosed |
| US-5847132-A | Polytriazine derivatives containing polyalkylpiperidinyloxy or polyalkylpiperidinylamino groups | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998054177-A1 | BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998054176-A1 | BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-12-03 | — | — | WO | disclosed |
| EP-0850938-A1 | Triazine compounds containing 2,2,6,6-tetramenthyl-4-piperidyl groups as stabilizers for organic materials | Ciba SC Holding AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| EP-0782994-A1 | Block oligomers containing 2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials | Ciba SC Holding AG (CH) | 1997-07-09 | — | — | EP | disclosed |
| US-5030729-A | Stabilizing Polyolefins Against Oxidative, Thermal And-Or Light Induced Degradation | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| US-4927925-A | Piperidine compounds and their use as thermal stabilizers | CIBA-GEIGY CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| US-4803234-A | Piperidine compounds and their use as anti-oxidative, light or thermal induced degradation agents | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4751281-A | LIGHT, HEAT, AND OXIDATION STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |