Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435630 | 0.78 | LAP3 (0.40) | LAP3FDPS | |
| SCHEMBL2686094 | 0.74 | LAP3 (0.32) | LAP3FDPS | |
| SCHEMBL9775319 | 0.72 | TRPM8 (0.31) | — | |
| SCHEMBL16616072 | 0.69 | — | — | |
| SCHEMBL8331137 | 0.62 | LMNA (0.38) | LAP3FDPS | |
| SCHEMBL22422704 | 0.60 | FDPS (0.40) | LAP3FDPS | |
| SCHEMBL19212090 | 0.60 | LAP3 (0.37) | LAP3FDPS | |
| SCHEMBL3889337 | 0.60 | GABBR2 (0.39) | LAP3FDPS | |
| SCHEMBL12570891 | 0.59 | FDPS (0.43) | LAP3FDPS | |
| SCHEMBL6831886 | 0.59 | LAP3 (0.46) | LAP3FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067702-B2 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | VRK1, VRK2, DEK | LAP3 4223/4885FDPS 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.