Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686094 | 0.80 | LAP3 (0.32) | LAP3GABBR2GABBR1FDPSLMNA | |
| SCHEMBL19212090 | 0.80 | LAP3 (0.37) | LAP3GABBR2GABBR1ANPEPGRM4 | |
| SCHEMBL18259703 | 0.78 | CYP3A4 (0.55) | FDPS | |
| SCHEMBL5873230 | 0.78 | LAP3 (0.31) | LAP3FDPS | |
| SCHEMBL9775319 | 0.78 | TRPM8 (0.31) | — | |
| SCHEMBL2986553 | 0.77 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL3889337 | 0.76 | GABBR2 (0.39) | LAP3GABBR2GABBR1ANPEPGRM4 | |
| SCHEMBL16616072 | 0.74 | — | — | |
| SCHEMBL746555 | 0.72 | LAP3 (0.43) | LAP3GABBR2GABBR1ANPEPERAP1 | |
| SCHEMBL19211944 | 0.72 | FDPS (0.33) | LAP3GABBR2GABBR1ANPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10060887-B2 | Field sampling kit and methods for collecting and detecting alkyl methylphosphonic acids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2018-08-28 | — | — | US | claimed |
| US-20120164027-A1 | Polymer Based Lanthanide Luminescent Sensors for the Detection of Organophosphorus Compounds | MURRAY GEORGE M (US) | 2012-06-28 | — | — | US | claimed |
| EP-1733211-B1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | UNIV JOHNS HOPKINS (US) | 2012-01-11 | — | — | EP | claimed |
| US-7416703-B2 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-08-26 | — | — | US | claimed |
| US-20050019218-A1 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | MURRAY GEORGE M (US) | 2005-01-27 | — | — | US | claimed |
| US-6403329-B1 | MIXING AND REACTING ALKYLOXY METHYLPHOSPHONIC ACID WITH DEHYDRATION AGENT TO MAKE CHOLINESTERASE INHIBITOR | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2002-06-11 | — | — | US | claimed |
| US-5935862-A | DETECTING PRESENCE OF CHEMICAL WARFARE AGENTS BY APPLYING LIQUID SAMPLE TO CHROMATOGRAPHIC ADSORBANT MATERIAL AND DETECTOR AGENT USING MICROCAPILLARY TUBE, FORMING CHROMOGENIC INDICATOR; PORTABLE, SENSITIVE, ACCURATE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1999-08-10 | — | — | US | claimed |
| US-12510908-B2 | Integration of metal-organic frameworks on textile fibers and fabrics for the destruction of nerve agents under ambient humidity conditions | NORTHWESTERN UNIVERSITY (US) | 2025-12-30 | — | — | US | disclosed |
| US-12102991-B2 | Ligand-directed reticular synthesis of metal-organic frameworks having edge-transitive ALB network topologies | NORTHWESTERN UNIVERSITY (US) | 2024-10-01 | — | — | US | disclosed |
| US-20240141308-A1 | ORGANOPHOSPHORUS NERVE AGENT HYDROLYZING ENZYMES | GINKGO BIOWORKS, INC. (US) | 2024-05-02 | — | — | US | disclosed |
| US-20230048741-A1 | INTEGRATION OF METAL-ORGANIC FRAMEWORKS ON TEXTILE FIBERS AND FABRICS FOR THE DESTRUCTION OF NERVE AGENTS UNDER AMBIENT HUMIDITY CONDITIONS | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2023-02-16 | — | — | US | disclosed |
| US-11524266-B1 | Metal-organic framework/polymer foam composite materials and their uses in decontamination and/or ballistic protection | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2022-12-13 | — | — | US | disclosed |
| WO-2022256087-A2 | ORGANOPHOSPHORUS NERVE AGENT HYDROLYZING ENZYMES | GINKGO BIOWORKS, INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| US-6403329-B1 | MIXING AND REACTING ALKYLOXY METHYLPHOSPHONIC ACID WITH DEHYDRATION AGENT TO MAKE CHOLINESTERASE INHIBITOR | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2002-06-11 | — | — | US | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5935862-A | DETECTING PRESENCE OF CHEMICAL WARFARE AGENTS BY APPLYING LIQUID SAMPLE TO CHROMATOGRAPHIC ADSORBANT MATERIAL AND DETECTOR AGENT USING MICROCAPILLARY TUBE, FORMING CHROMOGENIC INDICATOR; PORTABLE, SENSITIVE, ACCURATE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5689038-A | DETOXIFICATION CHEMICAL WAREFARE AGENTS USING ABSORBENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1997-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240141308-A1 | ORGANOPHOSPHORUS NERVE AGENT HYDROLYZING ENZYMES | PGLS, PNKP, ACHE | LAP3 148/4885GABBR2 2910/4885GABBR1 2504/4885 |
| US-12510908-B2 | Integration of metal-organic frameworks on textile fibers and fabrics for the destruction of nerve agents under ambient humidity conditions | H1-10, ACHE, H1-4 | LAP3 3713/4885GABBR2 4106/4885GABBR1 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.