Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 9/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873699 | 0.84 | ESR1 (0.57) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL9763865 | 0.83 | RORC (0.54) | RORCESR1CNR1CNR2ESR2 | |
| SCHEMBL9717788 | 0.83 | RORC (0.58) | RORCESR1CNR1CNR2ESR2 | |
| SCHEMBL2637888 | 0.79 | RORC (0.57) | RORCESR1CNR1CNR2ESR2 | |
| SCHEMBL14760247 | 0.78 | ALOX15 (0.54) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL10935943 | 0.78 | ESR1 (0.54) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL7972245 | 0.78 | ESR1 (0.54) | ESR1ESR2ARLMNA | |
| SCHEMBL15425831 | 0.78 | CHEK1 (0.65) | RORCESR1ESR2CHEK1FYN | |
| SCHEMBL6239606 | 0.78 | CNR1 (0.52) | RORCESR1CNR1CNR2ESR2 | |
| SCHEMBL313270 | 0.78 | RORC (0.51) | RORCESR1CNR1CNR2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500131-A2 | Polycarbonate resin solution for film formation by casting | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-08-26 | — | — | EP | disclosed |