Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL3872200 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1PABPC1UBE2NMAPT | |
| Quinoline SCHEMBL5527084 | 0.95 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1PABPC1UBE2NMAPT | |
| Trifluoroacetic Acid SCHEMBL22397327 | 0.88 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1UBE2NMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL5874587 | 0.87 | ALDH1A1 (0.65) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 | |
| Quinoline SCHEMBL28970061 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 | |
| Quinoline SCHEMBL5874493 | 0.86 | ALDH1A1 (0.77) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 | |
| Quinoline SCHEMBL372690 | 0.86 | ALDH1A1 (0.77) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 | |
| Quinoline SCHEMBL5283313 | 0.86 | ALDH1A1 (0.77) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 | |
| Quinoline SCHEMBL5875384 | 0.84 | ALDH1A1 (0.74) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 | |
| Quinoline SCHEMBL5272119 | 0.84 | ALDH1A1 (0.74) | ALDH1A1PABPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480543-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. (IT) | 2012-08-01 | — | — | EP | claimed |
| EP-0562815-A1 | Aromatic hydrocarbons separation from aromatic/non-aromatic mixtures | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| EP-2480543-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. (IT) | 2012-08-01 | — | — | EP | disclosed |
| EP-2473563-A2 | REACTIVE CYANINE COMPOUNDS | Promega Corporation (US) | 2012-07-11 | — | — | EP | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |