Sugi Predict

Sugi Predict / Compounds / SCHEMBL5877657

SCHEMBL5877657

SCHEMBL5877657

O=P(OP(=O)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.56
▸ L3MBTL1 Q9Y468 3/20 0.56
▸ MEN1 O00255 4/20 0.52
▸ KMT2A Q03164 4/20 0.52
▸ CA2 P00918 1/20 0.50
▸ CA4 P22748 1/20 0.50
▸ CA5A P35218 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.48
▸ CFTR P13569 1/20 0.44
▸ LMNA P02545 1/20 0.43
▸ GAA P10253 3/20 0.42
▸ MAPT P10636 1/20 0.42
▸ ALPG P10696 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ NPY1R P25929 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ NPY2R P49146 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ TSHR P16473 3/20 0.41
▸ ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28534150 0.85 CA2 (0.54) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL29085471 0.85 CA2 (0.54) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL7277887 0.82 ALDH1A1 (0.56) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL28366762 0.81 L3MBTL1 (0.44) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL332078 0.78 L3MBTL1 (0.58) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL276503 0.78 ALDH1A1 (0.58) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL5606000 0.78 CA2 (0.52) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL29662176 0.78 ALDH1A1 (0.52) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL7414010 0.78 ALDH1A1 (0.52) ALDH1A1L3MBTL1MEN1KMT2ACA2
SCHEMBL16261346 0.78 ALDH1A1 (0.52) ALDH1A1L3MBTL1MEN1KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521282-A Synthetic process of coumarin compound E-Suberenol 大理大学 2022-12-27 — — CN claimed
CN-115477630-A Coumarin derivatives and preparation method thereof 大理大学 2022-12-16 — — CN claimed
CN-115477631-A Synthesis method of compound containing dimethyl enol group 大理大学 2022-12-16 — — CN claimed
CN-115232094-A Synthetic method of coumarin compound Murroal 大理大学 2022-10-25 — — CN claimed
CN-115058185-A Flame-retardant waterborne polyurethane paint and synthesis method thereof 薛庆霞 2022-09-16 — — CN claimed
CN-114957120-A Alkenyl homopiperidine compound and preparation method thereof 苏州大学 2022-08-30 — — CN claimed
CN-113880834-A Synthesis method of N- (phenylsulfonyl) benzamide compound and intermediate thereof 苏州亚盛药业有限公司 2022-01-04 — — CN claimed
CN-112920033-A Preparation method of o-alkynyl phenylcyclobutanone and preparation method of naphthalenone 长春工业大学 2021-06-08 — — CN claimed
CN-111892590-A New piparib new intermediate, crystal form and preparation method thereof 齐鲁制药有限公司 2020-11-06 — — CN claimed
CN-108467408-B Diaryl phosphorus compound with hydroxyphenyl functional group and preparation method thereof 东北大学 2020-07-17 — — CN claimed
CN-111303162-A Preparation method of 2-chloro-7-cyclopentyl-7H-pyrrolo [2,3-d ] pyrimidine-6-carboxylic acid 天津法莫西医药科技有限公司 2020-06-19 — — CN claimed
EP-4735424-A1 PROCESSES FOR MAKING IRAK4 INHIBITORS GILEAD SCIENCES, INC. (US) 2026-05-06 — — EP disclosed
US-20250296933-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. 2025-09-25 — — US disclosed
US-20250042906-A1 PROCESSES FOR MAKING IRAK4 INHIBITORS GILEAD SCIENCES, INC. 2025-02-06 — — US disclosed
WO-2025006946-A1 PROCESSES FOR MAKING IRAK4 INHIBITORS GILEAD SCIENCES, INC. (US) 2025-01-02 — — WO disclosed
EP-0257380-A2 Process for the preparation of thiophosphinic acid chlorides HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-02 — — EP disclosed
EP-0075233-B1 SELF-EXTINGUISHIBLE THERMOPLASTIC MOULDING MASSES BASF Aktiengesellschaft (DE) 1984-12-19 — — EP disclosed
US-4481151-A Process for the preparation of dialkylphosphinic acid halides HOECHST AKTIENGESELLSCHAFT (DE) 1984-11-06 — — US disclosed
EP-0075233-A1 Self-extinguishible thermoplastic moulding masses BASF Aktiengesellschaft (DE) 1983-03-30 — — EP disclosed
US-4138433-A Process for preparing 1,2-oxa-phospholanes HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042906-A1 PROCESSES FOR MAKING IRAK4 INHIBITORS IRAK4, IRAK3, IRAK2 ALDH1A1 4273/4885L3MBTL1 939/4885MEN1 3102/4885
US-20250296933-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS CYP11B1, CYP11A1, CYP11B2 ALDH1A1 205/4885L3MBTL1 4343/4885MEN1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.