Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGAV | P06756 | 9/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879517 | 0.75 | ITGB3 (0.72) | ITGB3ITGAV | |
| SCHEMBL5879664 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVTP53ALDH1A1 | |
| SCHEMBL5879778 | 0.74 | ITGB3 (0.43) | ITGB3ITGAVTHRBALDH1A1 | |
| SCHEMBL5879795 | 0.74 | ITGB3 (0.73) | ITGB3ITGAVALDH1A1 | |
| SCHEMBL5879751 | 0.71 | ITGB3 (0.49) | ITGB3ITGAVTP53THRBALDH1A1 | |
| SCHEMBL5879845 | 0.70 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL5879698 | 0.70 | ITGB3 (0.71) | ITGB3ITGAV | |
| SCHEMBL5879558 | 0.69 | ITGB3 (0.74) | ITGB3ITGAVTHRBPOLB | |
| SCHEMBL5879569 | 0.69 | ITGB3 (0.51) | ITGB3ITGAVTHRB | |
| SCHEMBL5879625 | 0.68 | ITGB3 (0.61) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |