Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGAV | P06756 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879664 | 0.80 | ITGB3 (0.52) | ITGB3ITGAVALDH1A1MEN1KMT2A | |
| SCHEMBL5879692 | 0.76 | NOS2 (0.48) | ITGB3ITGAVALDH1A1MEN1KMT2A | |
| SCHEMBL5879558 | 0.75 | ITGB3 (0.74) | ITGB3ITGAVKDM4EGAATHRB | |
| SCHEMBL5879569 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVKDM4ETHRBNPC1 | |
| SCHEMBL5879621 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879673 | 0.72 | HSD17B10 (0.63) | CYP2C19ALDH1A1KMT2ANPSR1KDM4E | |
| SCHEMBL5879592 | 0.71 | ITGB3 (0.43) | ITGB3ITGAVALDH1A1THRBTP53 | |
| SCHEMBL5879778 | 0.70 | ITGB3 (0.43) | ITGB3ITGAVALDH1A1KMT2AKDM4E | |
| SCHEMBL5879510 | 0.69 | GRIN2B (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL5879740 | 0.68 | ITGB3 (0.67) | ITGB3ITGAVKDM4ETHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |