Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.51 |
| ▸ | ITGAV | P06756 | 12/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879621 | 0.86 | ITGB3 (0.51) | ITGB3ITGAVKDM4ETHRBMAPK1 | |
| SCHEMBL5879553 | 0.84 | ITGB3 (0.47) | ITGB3ITGAVKDM4ELMNA | |
| SCHEMBL5879558 | 0.82 | ITGB3 (0.74) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879645 | 0.74 | ITGB3 (0.61) | ITGB3ITGAVKDM4EHTTNPC1 | |
| SCHEMBL5879664 | 0.73 | ITGB3 (0.52) | ITGB3ITGAVKDM4ELMNA | |
| SCHEMBL5879778 | 0.73 | ITGB3 (0.43) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879692 | 0.73 | NOS2 (0.48) | ITGB3ITGAVKDM4EMAPT | |
| SCHEMBL5879751 | 0.73 | ITGB3 (0.49) | ITGB3ITGAVKDM4ETHRBNPC1 | |
| SCHEMBL5879698 | 0.71 | ITGB3 (0.71) | ITGB3ITGAVNPC1MAPTRAB9A | |
| SCHEMBL5879538 | 0.70 | ITGB3 (0.73) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |