Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGAV | P06756 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 2/20 | 0.39 |
| ▸ | SKP1 | P63208 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879601 | 0.92 | HSD17B10 (0.45) | ITGB3ITGAVHSD17B10KDM4ECKS1B | |
| SCHEMBL5879673 | 0.83 | HSD17B10 (0.63) | HSD17B10KDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5879845 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVKMT2A | |
| SCHEMBL5879731 | 0.78 | HSD17B10 (0.64) | HSD17B10KDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5879692 | 0.75 | NOS2 (0.48) | ITGB3ITGAVHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5879592 | 0.74 | ITGB3 (0.43) | ITGB3ITGAVTHRBALDH1A1 | |
| SCHEMBL5879563 | 0.74 | POLB (0.45) | ITGB3ITGAVKDM4EKMT2A | |
| SCHEMBL5879569 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879558 | 0.72 | ITGB3 (0.74) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879664 | 0.71 | ITGB3 (0.52) | ITGB3ITGAVKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |