Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13167384 | 0.87 | HTT (0.48) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| SCHEMBL4454372 | 0.81 | TNKS (0.53) | SMN1; SMN2POLBMAPTLMNAALDH1A1 | |
| SCHEMBL305355 | 0.78 | POLB (0.64) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| SCHEMBL6948812 | 0.78 | PKM (0.58) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| SCHEMBL4347806 | 0.77 | RIPK1 (0.43) | SMN1; SMN2KMT2ARAB9AMAPTLMNA | |
| SCHEMBL5264712 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2POLBRAB9AMAPTLMNA | |
| SCHEMBL23705616 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| SCHEMBL14616208 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| Hydrochloric Acid SCHEMBL27826900 | 0.77 | POLB (0.63) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| SCHEMBL7002587 | 0.77 | GAA (0.42) | SMN1; SMN2KMT2APOLBRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |
| EP-1202988-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010847-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |