Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885894 | 1.00 | SIGMAR1 (0.55) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL5885695 | 0.84 | ADRA1D (0.59) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL13984210 | 0.84 | ADRA1D (0.59) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL30063021 | 0.84 | ADRA1D (0.59) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL5885698 | 0.84 | ADRA1D (0.59) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL28441227 | 0.84 | ADRA1D (0.59) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL28441225 | 0.84 | ADRA1D (0.59) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| Hydrochloric Acid SCHEMBL28440129 | 0.83 | ADRA1D (0.58) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| Hydrochloric Acid SCHEMBL9416386 | 0.83 | ADRA1D (0.58) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL6135589 | 0.79 | SIGMAR1 (0.57) | SIGMAR1ADRA1DADRA1AADRA1BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084301-B2 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-01 | — | — | US | disclosed |
| US-20050154231-A1 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-14 | — | — | US | disclosed |
| US-6894188-B1 | Tamsulosin derivative | RANBAXY LABORATORY LIMITED (IN) | 2005-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154231-A1 | Tamsulosin derivative | ADRB1, ADRA1B, ADRA2B | SIGMAR1 532/4885ADRA1D 5/4885ADRA1A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.