Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135591 | 1.00 | SIGMAR1 (0.57) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL6135925 | 0.85 | ADRA1D (0.73) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL6135926 | 0.85 | ADRA1D (0.73) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL15305044 | 0.82 | ADRA1A (0.47) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL11873153 | 0.80 | LMNA (0.45) | SIGMAR1ADRA1DADRA1AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11880845 | 0.79 | KDM4E (0.46) | SIGMAR1ADRA1DADRA1AADRB2ADRB1 | |
| SCHEMBL5885901 | 0.79 | SIGMAR1 (0.55) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL5885894 | 0.79 | SIGMAR1 (0.55) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL4869574 | 0.79 | ADRA1A (0.80) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 | |
| Hydrochloric Acid SCHEMBL9124000 | 0.78 | ADRA1A (0.75) | SIGMAR1ADRA1DADRA1AADRA1BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501793-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES, LTD. (IN) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093227-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES LIMITED (IN) | 2003-11-13 | — | — | WO | disclosed |