Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.34 |
| ▸ | MICA | Q29983 | 1/20 | 0.34 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502544 | 0.79 | GPR55 (0.39) | SMN1; SMN2KDM4EPOLBNPC1RAB9A | |
| SCHEMBL5121903 | 0.70 | AHR (0.45) | AHRCYP1B1ALDH1A1KDM4ENPC1 | |
| SCHEMBL394514 | 0.70 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL4810970 | 0.68 | AHR (0.46) | AHRCYP1B1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29402881 | 0.65 | TSHR (0.61) | KIF20BAHRKMT2ARAD51ALDH1A1 | |
| SCHEMBL980201 | 0.65 | TSHR (0.61) | KIF20BAHRKMT2ARAD51ALDH1A1 | |
| SCHEMBL403256 | 0.64 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2KDM4EPOLBL3MBTL1 | |
| SCHEMBL2120862 | 0.64 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2KDM4EPOLB | |
| Ammonia Solution, Strong SCHEMBL28020319 | 0.63 | TSHR (0.58) | KIF20BAHRKMT2ARAD51ALDH1A1 | |
| SCHEMBL1034476 | 0.63 | AGBL2 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | claimed |