Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889312 | 0.89 | NOS1 (0.49) | NOS1NOS2CHRNB4CHRNA3MAOA | |
| SCHEMBL14457840 | 0.77 | MAOA (0.47) | NOS1NOS2MAOAMAOBMEN1 | |
| SCHEMBL14457932 | 0.77 | NOS1 (0.42) | NOS1NOS2MAOBMEN1KMT2A | |
| SCHEMBL14457906 | 0.77 | ALDH1A1 (0.44) | NOS1NOS2TAAR1MEN1KMT2A | |
| SCHEMBL7852010 | 0.75 | CHRNB2 (0.44) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL17309174 | 0.75 | MAOB (0.49) | NOS2MAOAMAOBTAAR1MEN1 | |
| Hydrochloric Acid SCHEMBL11719754 | 0.74 | NOS2 (0.90) | NOS1NOS2MAOAMAOBTAAR1 | |
| SCHEMBL14457874 | 0.74 | CHRNB4 (0.45) | NOS1NOS2CHRNB4CHRNA3MAOA | |
| SCHEMBL5889318 | 0.74 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL20080246 | 0.73 | MAOB (0.40) | NOS1NOS2CHRNB4CHRNA3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017011531-A2 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-19 | — | — | WO | disclosed |
| US-7122506-B2 | Cyclic imines as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2006-10-17 | — | — | US | disclosed |
| EP-1077938-B1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| US-20040186287-A1 | Cyclic imines as pesticides | PLANT ANDREW (DE) | 2004-09-23 | — | — | US | disclosed |
| EP-1080072-B1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-08-04 | — | — | EP | disclosed |
| US-6770595-B2 | ACTIVITY AGAINST ARTHROPODS IN AGRICULTURE AND PARASITES ENCOUNTERED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| US-6632833-B1 | Their preparation and to their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| US-6599924-B1 | 2-hetaryl-3,4 dihydro-2H-pyrrole pesticide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| EP-1306371-A1 | Cyclic imines | Bayer CropScience AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| EP-1306371-A1 | Cyclic imines | Bayer CropScience AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6399771-B1 | AGRICULTURE; VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-04 | — | — | US | disclosed |
| US-6274613-B1 | APPLYING COMPOUNDS SUCH AS A GAMMA-ETHOXY-GAMMA-BUTYROLACTAM TO PESTS AND/OR THEIR HABITATS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-14 | — | — | US | disclosed |
| EP-1121357-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1080072-A1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-03-07 | — | — | EP | disclosed |
| EP-1077938-A1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000021958-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999059968-A1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999059967-A1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0942901-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022438-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186287-A1 | Cyclic imines as pesticides | DDT, CYP1A1, AR | NOS1 2198/4885NOS2 3217/4885CHRNB4 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.