Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12555528 | 0.98 | CASP6 (0.57) | CASP6CA1CA2CA9ALDH1A1 | |
| Pyridine SCHEMBL5891724 | 0.87 | CASP6 (0.51) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL2626664 | 0.83 | CA1 (0.53) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL30139067 | 0.83 | LMNA (0.55) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL5891034 | 0.83 | LMNA (0.55) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL2639424 | 0.83 | CA1 (0.71) | CA1CA2CA9ALDH1A1HPGD | |
| SCHEMBL27467793 | 0.83 | MEN1 (0.53) | CASP6CA1CA2ALDH1A1BACE1 | |
| SCHEMBL9651923 | 0.81 | CA2 (0.47) | CASP6CA1CA2CA9LMNA | |
| SCHEMBL149505 | 0.80 | CA1 (0.74) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL11638608 | 0.80 | CA1 (0.77) | CASP6CA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358404-B | Preparation method of 2-chloro-6-methylaniline | 扬州市普林斯医药科技有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-112358404-A | Preparation method of 2-chloro-6-methylaniline | 扬州市普林斯医药科技有限公司 | 2021-02-12 | — | — | CN | disclosed |
| US-6995283-B2 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-07 | — | — | US | disclosed |
| US-20060009651-A1 | Benzophenones as inhibitors of reverse transcriptase | CHAN JOSEPH H | 2006-01-12 | — | — | US | disclosed |
| US-20040122064-A1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION | 2004-06-24 | — | — | US | disclosed |
| EP-1363877-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070470-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009651-A1 | Benzophenones as inhibitors of reverse transcriptase | POLRMT, ELL, POLR2A | CASP6 1957/4885CA1 4866/4885CA2 4784/4885 |
| US-20040122064-A1 | Benzophenones as inhibitors of reverse transcriptase | POLRMT, ELL, POLR2A | CASP6 1957/4885CA1 4866/4885CA2 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.