SCHEMBL8897534

SCHEMBL8897534

CCOC(=O)COc1ccc(C(=O)C(CC)(Cc2ccccc2)N(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
LTA4H P09960 3/20 0.43
MLYCD O95822 1/20 0.43
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPK1 P28482 2/20 0.43
ESR1 P03372 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156794 0.83 NPY5R (0.47) HPGDALDH1A1POLBRAB9ANPC1
SCHEMBL5897070 0.83 GAA (0.50) MAPTALDH1A1GAARAB9ANPC1
SCHEMBL28032703 0.82 NPY5R (0.49) HPGDALDH1A1POLBRAB9ANPC1
SCHEMBL4651504 0.82 ACHE (0.51) HPGDMAPTKDM4EALDH1A1NPSR1
SCHEMBL8899954 0.81 CHRNB2 (0.44) MAPTKDM4EPOLBRAB9ANPC1
SCHEMBL4651747 0.81 NPC1 (0.41) HPGDMAPTKDM4EALDH1A1LMNA
SCHEMBL4650526 0.80 RIPK1 (0.43) LMNAMLYCDRAB9ANPC1SMN1; SMN2
Benzene SCHEMBL28672020 0.80 RIPK1 (0.43) LMNAMLYCDRAB9ANPC1SMN1; SMN2
SCHEMBL1554156 0.78 NPY5R (0.46) HPGDALDH1A1POLBRAB9ANPC1
SCHEMBL8899758 0.78 PPARG (0.48) MAPTTP53MLYCDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed