Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029939 | 0.77 | GRIA2 (0.32) | RIPK1GRIA2GRIA4PGR | |
| SCHEMBL22648150 | 0.76 | PGR (0.33) | KMT2AALDH1A1MEN1MAPTPGR | |
| SCHEMBL9943768 | 0.73 | DAO (0.45) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24992381 | 0.69 | KDM4E (0.34) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL3960184 | 0.68 | DAO (0.48) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6323918 | 0.68 | GPR119 (0.39) | PGR | |
| SCHEMBL5879615 | 0.68 | GPR35 (0.36) | NSD2KMT2A | |
| SCHEMBL352339 | 0.67 | L3MBTL1 (0.56) | RIPK1ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL7205892 | 0.67 | F2 (0.52) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5903739 | 0.65 | ALDH1A1 (0.60) | KMT2AALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125883-B1 | Integrin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2006-10-24 | — | — | US | disclosed |