Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | BMP1 | P13497 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899440 | 0.87 | TAS2R14 (0.63) | HSD11B1TAS2R14MEN1KMT2A | |
| SCHEMBL5899445 | 0.83 | TAS2R14 (0.66) | TAS2R14MEN1KMT2ADAGLA | |
| SCHEMBL5899551 | 0.82 | TAS2R14 (0.56) | BMP1TAS2R14MEN1KMT2AKEAP1 | |
| SCHEMBL8064179 | 0.82 | TAS2R14 (0.55) | PTPN1HSD11B1TAS2R14MEN1KMT2A | |
| SCHEMBL5899564 | 0.79 | HSD11B1 (0.51) | MMP1HSD11B1TAS2R14MEN1KMT2A | |
| SCHEMBL1287322 | 0.75 | MEN1 (0.65) | TAS2R14MEN1KMT2A | |
| SCHEMBL1169357 | 0.74 | TAS2R14 (0.75) | TAS2R14MEN1KMT2ADAGLA | |
| SCHEMBL5295487 | 0.73 | TAS2R14 (0.64) | HSD11B1TAS2R14MEN1KMT2AKEAP1 | |
| SCHEMBL1951391 | 0.73 | HSD11B1 (0.56) | PTPN1HSD11B1TAS2R14MEN1KMT2A | |
| SCHEMBL8064181 | 0.73 | MAPT (0.54) | PTPN1TAS2R14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | PTPN1 2903/4885MMP1 369/4885BMP1 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.