Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 11/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899445 | 0.90 | TAS2R14 (0.66) | TAS2R14MEN1KMT2ACXCR3ALDH1A1 | |
| SCHEMBL5899564 | 0.89 | HSD11B1 (0.51) | TAS2R14MEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL5899551 | 0.87 | TAS2R14 (0.56) | TAS2R14MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5899442 | 0.87 | PTPN1 (0.57) | TAS2R14MEN1KMT2AHSD11B1 | |
| SCHEMBL5295487 | 0.85 | TAS2R14 (0.64) | TAS2R14MEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL984791 | 0.81 | TAS2R14 (0.71) | TAS2R14MEN1KMT2AHSD11B1CXCR3 | |
| SCHEMBL2845552 | 0.80 | MEP1B (0.68) | TAS2R14MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4540959 | 0.79 | MEN1 (0.64) | TAS2R14MEN1KMT2ACXCR3ALDH1A1 | |
| SCHEMBL3814018 | 0.79 | TAS2R14 (0.73) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1278616 | 0.78 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | TAS2R14 4454/4885MEN1 1269/4885KMT2A 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.