Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899592 | 0.89 | MMP8 (0.52) | CA1CA2CA12CA9HDAC3 | |
| SCHEMBL7674553 | 0.80 | HSD11B1 (0.57) | CA1CA2CA12CA9HDAC3 | |
| SCHEMBL5899460 | 0.79 | TSHR (0.61) | CA1CA2CA12CA9HDAC3 | |
| SCHEMBL24443525 | 0.78 | HDAC3 (0.58) | CA1CA2CA12CA9HDAC3 | |
| SCHEMBL3852945 | 0.78 | HDAC3 (0.61) | CA1CA2CA12CA9HDAC3 | |
| SCHEMBL23014131 | 0.77 | ALDH1A1 (0.57) | CA1CA2CA12CA9HDAC3 | |
| SCHEMBL7983736 | 0.77 | CA1 (0.62) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL5899494 | 0.77 | ALDH1A1 (0.59) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL153386 | 0.77 | ALDH1A1 (0.76) | CA1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL21115781 | 0.76 | HSD11B1 (0.64) | CA1CA2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | CA1 1910/4885CA2 3489/4885CA12 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.