Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736507 | 0.87 | PTGIR (0.63) | PTGIRKDM4EALDH1A1POLBTSHR | |
| SCHEMBL5908140 | 0.85 | PTGIR (0.46) | PTGIRKDM4EALDH1A1POLBTSHR | |
| SCHEMBL7737053 | 0.83 | HTR1A (0.49) | PTGIRTSHRHTR1ASLC6A4ALPL | |
| SCHEMBL13545370 | 0.74 | CYSLTR2 (0.40) | PTGIRALDH1A1POLBTSHRHTR1A | |
| SCHEMBL7739676 | 0.73 | PTGIR (0.55) | PTGIRKDM4EALDH1A1POLBTSHR | |
| SCHEMBL7737336 | 0.73 | PTGIR (0.70) | PTGIRKDM4EALDH1A1POLBTSHR | |
| SCHEMBL7737108 | 0.72 | PTGIR (0.57) | PTGIRKDM4EALDH1A1POLBTSHR | |
| SCHEMBL7729866 | 0.72 | DRD2 (0.38) | PTGIRTSHRHTR1ASLC6A4CYSLTR2 | |
| SCHEMBL7729950 | 0.72 | PTGIR (0.58) | PTGIRKDM4EALDH1A1POLBHTR1A | |
| SCHEMBL7736529 | 0.72 | PTGIR (0.56) | PTGIRKDM4EALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040931-A1 | Benzomorpholine derivatives | TORAY INDUSTRIES, INC. (JP) | 2006-02-23 | — | — | US | disclosed |
| CN-1735603-A | The benzo morpholine derivative | TORAY INDUSTRIES (JP) | 2006-02-15 | — | — | CN | disclosed |
| EP-1574504-A1 | BENZOMORPHOLINE DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 2005-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040931-A1 | Benzomorpholine derivatives | PF4, TFPI, TBXA2R | PTGIR 69/4885KDM4E 2081/4885ALDH1A1 1451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.