SCHEMBL5908181

SCHEMBL5908181

Cc1ccccc1COc1ccc(Cc2ccccc2C)cc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 4/20 0.62
▸ ALDH1A1 P00352 3/20 0.51
▸ FFAR4 Q5NUL3 2/20 0.50
▸ CFD P00746 1/20 0.50
▸ THRA P10827 1/20 0.49
▸ THRB P10828 1/20 0.49
▸ RXRA P19793 1/20 0.48
▸ RXRB P28702 1/20 0.48
▸ RXRG P48443 1/20 0.48
▸ FFAR1 O14842 1/20 0.47
▸ MRGPRX4 Q96LA9 3/20 0.47
▸ GAA P10253 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ KMT2A Q03164 1/20 0.45
▸ PTGER1 P34995 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5839145 0.83 ALDH1A1 (0.68) FOLH1ALDH1A1RXRARXRBRXRG
SCHEMBL9650182 0.79 HNF4A (0.69) KMT2AHTT
SCHEMBL9158071 0.79 FOLH1 (0.76) FOLH1ALDH1A1FFAR4CFDFFAR1
SCHEMBL25642477 0.76 CFD (0.54) FOLH1ALDH1A1CFDMRGPRX4GAA
SCHEMBL28807829 0.75 THRA (0.48) ALDH1A1THRATHRBMRGPRX4MAPT
SCHEMBL5291219 0.74 HTT (0.68) FOLH1ALDH1A1RXRARXRBRXRG
SCHEMBL28638554 0.73 ALDH1A1 (0.62) FOLH1ALDH1A1RXRARXRBRXRG
SCHEMBL9557982 0.73 CFD (0.66) FOLH1ALDH1A1CFDMRGPRX4KMT2A
SCHEMBL6369577 0.73 HMGB1 (0.73) ALDH1A1KMT2AKDM4EHTT
SCHEMBL1647381 0.73 FOLH1 (0.67) FOLH1ALDH1A1FFAR4RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3263553-B1 CRYSTALLINE MODIFICATION OF N-(2-(3-PHENYLUREIDO)PHENYL)BENZENESULFONAMIDE AND RECORDING MATERIAL USING SAME NIPPON SODA CO (JP) 2020-12-09 — — EP disclosed
EP-2923851-B1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO (JP) 2019-05-01 — — EP disclosed
US-10265984-B2 Crystalline modification of N-(2-(3-phenylureido)phenyl)benzenesulfonamide and recording material using same NIPPON SODA CO., LTD. (JP) 2019-04-23 — — US disclosed
US-20180022136-A1 CRYSTALLINE MODIFICATION OF N-(2-(3-PHENYLUREIDO)PHENYL)BENZENESULFONAMIDE AND RECORDING MATERIAL USING SAME NIPPON SODA CO., LTD. (JP) 2018-01-25 — — US disclosed
EP-3263553-A1 CRYSTALLINE MODIFICATION OF N-(2-(3-PHENYLUREIDO)PHENYL)BENZENESULFONAMIDE AND RECORDING MATERIAL USING SAME Nippon Soda Co., Ltd. (JP) 2018-01-03 — — EP disclosed
EP-2923851-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND Nippon Soda Co., Ltd. (JP) 2015-09-30 — — EP disclosed
US-20060063669-A1 Recording material comprising diphenyl sulfone derivative and novel diphenyl sulfone derivative compound NIPPON SODA CO., LTD. (JP) 2006-03-23 — — US disclosed
EP-1557408-A1 RECORDING MATERIAL COMPRISING DIPHENYL SULFONE DERIVATIVE AND NOVEL DIPHENYL SULFONE DERIVATIVE COMPOUND NIPPON SODA CO., LTD. (JP) 2005-07-27 — — EP disclosed
EP-0860429-B1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO (JP) 2001-12-12 — — EP disclosed
EP-0906908-A1 TRIAZINE DERIVATIVES AND RECORDING MATERIALS PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1999-04-07 — — EP disclosed
EP-0860429-A1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO., LTD. (JP) 1998-08-26 — — EP disclosed
EP-0380677-B1 FLUORAN COMPOUNDS AND COLOR-FORMING RECORDING MATERIALS CONTAINING SAME NIPPON SODA CO (JP) 1995-11-22 — — EP disclosed
US-5017710-A Solubility, storage stability NIPPON SODA CO., LTD. (JP) 1991-05-21 — — US disclosed
EP-0380677-A1 FLUORAN COMPOUNDS AND COLOR-FORMING RECORDING MATERIALS CONTAINING SAME NIPPON SODA CO., LTD. (JP) 1990-08-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10265984-B2 Crystalline modification of N-(2-(3-phenylureido)phenyl)benzenesulfonamide and recording material using same PDXK, PRNP, UCK2 FOLH1 3804/4885ALDH1A1 3472/4885FFAR4 3671/4885
US-20180022136-A1 CRYSTALLINE MODIFICATION OF N-(2-(3-PHENYLUREIDO)PHENYL)BENZENESULFONAMIDE AND RECORDING MATERIAL USING SAME PDXK, PRNP, UCK2 FOLH1 3804/4885ALDH1A1 3472/4885FFAR4 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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