Dinitro Cresol

Dinitro Cresol

SCHEMBL591998

Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.71
GPR35 Q9HC97 4/20 0.71
MEN1 O00255 7/20 0.55
KMT2A Q03164 7/20 0.55
HSP90AA1 P07900 1/20 0.55
HPGD P15428 3/20 0.53
ALOX12 P18054 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
GAA P10253 2/20 0.51
MAPT P10636 6/20 0.49
MAPK1 P28482 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
KDM4E B2RXH2 3/20 0.49
ALOX15 P16050 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TTR P02766 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
RECQL P46063 1/20 0.49
PMP22 Q01453 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitro Cresol SCHEMBL7533175 0.90 ALDH1A1 (0.61) ALDH1A1GPR35MEN1KMT2AHSP90AA1
Dinitro Cresol SCHEMBL5068722 0.89 GPR35 (0.68) ALDH1A1GPR35MEN1KMT2AHSP90AA1
Dinitro Cresol SCHEMBL1716451 0.88 GPR35 (0.93) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL1509581 0.87 GPR35 (0.78) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL892354 0.87 ALDH1A1 (0.78) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL3976321 0.87 GPR35 (0.78) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL2549698 0.86 GPR35 (0.89) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL6859521 0.86 GPR35 (0.96) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL9221013 0.85 ALDH1A1 (0.81) ALDH1A1GPR35MEN1KMT2AHPGD
Dinitro Cresol SCHEMBL4735684 0.85 GPR35 (0.81) ALDH1A1GPR35MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170023681-A1 PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER NEW YORK UNIVERSITY 2017-01-26 US disclosed
CN-104262193-B A kind of dinitro diphenylamine diazo resin, photoetching compositions containing this resin and preparation method thereof 京东方科技集团股份有限公司 2016-06-08 CN disclosed
CN-104262193-B A kind of dinitro diphenylamine diazo resin, photoetching compositions containing this resin and preparation method thereof 京东方科技集团股份有限公司 2016-06-08 CN disclosed
CN-104262193-B A kind of dinitro diphenylamine diazo resin, photoetching compositions containing this resin and preparation method thereof 京东方科技集团股份有限公司 2016-06-08 CN disclosed
US-9086489-B2 Personal and area self-indicating instant radiation alert dosimeter JP LABORATORIES, INC (US) 2015-07-21 US disclosed
CN-104262193-A Dinitrodiphenylamine diazoresin, photoresist composition containing same and preparation method of photoresist composition BOE TECHNOLOGY GROUP CO LTD 2015-01-07 CN disclosed
US-8872134-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC (US) 2014-10-28 US disclosed
CN-102686553-A Production method for 4,4'-bis(alkylamino)diphenylamine KOREA KUMHO PETROCHEM CO LTD 2012-09-19 CN disclosed
US-20120205591-A1 SELF INDICATING RADIATION ALERT DOSIMETER PATEL GORDHABHAI N (US) 2012-08-16 US disclosed
US-20120181453-A1 PERSONAL AND AREA SELF-INDICATING INSTANT RADIATION ALERT DOSIMETER JP LABORATORIES INC. 2012-07-19 US disclosed
EP-1281080-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2003-02-05 EP disclosed
EP-1200135-A1 MONITORING METHOD FOR STERILIZATION WITH ETHYLENE OXIDE Patel, Gordhanbhai N. (US) 2002-05-02 EP disclosed
EP-1165151-A1 INDICATORS FOR MONITORING STERILIZATION WITH PLASMA Patel, Gordhanbhai N. (US) 2002-01-02 EP disclosed
WO-2001086289-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2001-11-15 WO disclosed
CN-1298866-A Preph. of 4,4'-dinitro diphenylamine from urea and nitrobenzene KVM HO PETRO CHEMICAL CO LTD (KR) 2001-06-13 CN disclosed
WO-2001010471-A1 DOSIMETER FOR STERILIZATION WITH ETHYLENE OXIDE PATEL GORDHANBHAI N (US) 2001-02-15 WO disclosed
WO-2000061200-A1 INDICATORS FOR MONITORING STERILIZATION WITH PLASMA PATEL GORDHANBHAI N (US) 2000-10-19 WO disclosed
CN-1092408-A Process for the preparation of isocyanate and carbamate products MONSANTO CO (US) 1994-09-21 CN disclosed
US-4112229-A Diphenylamines for dyeing keratinous fibers L'OREAL (FR) 1978-09-05 US disclosed
US-4042627-A HAIR DYES L'OREAL (FR) 1977-08-16 US disclosed