Dinitro Cresol

Dinitro Cresol

SCHEMBL7533175

Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O.O=[N+]([O-])c1ccc(Nc2ccccc2)c([N+](=O)[O-])c1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
GPR35 Q9HC97 1/20 0.61
MEN1 O00255 8/20 0.56
KMT2A Q03164 8/20 0.56
GFER P55789 2/20 0.56
MAPT P10636 8/20 0.55
MAPK1 P28482 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
HCAR3 P49019 1/20 0.54
CTSV O60911 1/20 0.54
CTSL P07711 1/20 0.54
POLB P06746 2/20 0.50
CXCR1 P25024 1/20 0.50
CXCR2 P25025 1/20 0.50
CASP7 P55210 1/20 0.50
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
THRB P10828 1/20 0.48
HSP90AA1 P07900 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitro Cresol SCHEMBL591998 0.90 ALDH1A1 (0.71) ALDH1A1GPR35MEN1KMT2AMAPT
SCHEMBL293916 0.85 MAPT (0.72) ALDH1A1MEN1KMT2AGFERMAPT
SCHEMBL3272499 0.83 MAPT (0.73) ALDH1A1MEN1KMT2AGFERMAPT
Dinitro Cresol SCHEMBL5068722 0.82 GPR35 (0.68) ALDH1A1GPR35MEN1KMT2AMAPT
SCHEMBL11337250 0.81 MAPT (0.68) ALDH1A1MEN1KMT2AGFERMAPT
Dinitro Cresol SCHEMBL1716451 0.81 GPR35 (0.93) ALDH1A1GPR35MEN1KMT2AMAPT
Dinitro Cresol SCHEMBL3976321 0.80 GPR35 (0.78) ALDH1A1GPR35MEN1KMT2AMAPT
Dinitro Cresol SCHEMBL892354 0.80 ALDH1A1 (0.78) ALDH1A1GPR35MEN1KMT2AMAPT
Dinitro Cresol SCHEMBL1509581 0.80 GPR35 (0.78) ALDH1A1GPR35MEN1KMT2AMAPT
Dinitro Cresol SCHEMBL2549698 0.80 GPR35 (0.89) ALDH1A1GPR35MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194809-A1 ELECTRO-OPTICAL DEVICE AND VARIABLE TRANSPARENT ARTICLE WITH SUCH DEVICE PPG Industries Ohio, Inc. (US) 2002-04-10 EP disclosed
WO-2000077559-A1 ELECTRO-OPTICAL DEVICE AND VARIABLE TRANSPARENT ARTICLE WITH SUCH DEVICE PPG INDUSTRIES OHIO, INC. (US) 2000-12-21 WO disclosed