Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.47 |
| ▸ | LDHB | P07195 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.41 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925079 | 0.79 | LDHA (0.45) | LDHALDHBP4HA1P4HTMTSHR | |
| SCHEMBL5924626 | 0.75 | IDO1 (0.41) | TSHRALDH1A1POLBKMT2AL3MBTL1 | |
| SCHEMBL13117407 | 0.71 | KDM4C (0.59) | LDHALDHBTSHRKMOKDM4E | |
| SCHEMBL6252126 | 0.70 | P4HA1 (0.61) | LDHAP4HA1P4HTMTSHRSMN1; SMN2 | |
| SCHEMBL5924725 | 0.69 | TSHR (0.46) | LDHALDHBP4HA1P4HTMTSHR | |
| SCHEMBL5924630 | 0.68 | KCNH2 (0.35) | SMN1; SMN2HPGD | |
| SCHEMBL1018250 | 0.68 | P4HA1 (0.49) | LDHAP4HA1P4HTMSRD5A2KDM4E | |
| SCHEMBL4652654 | 0.67 | LDHA (0.62) | LDHAP4HA1P4HTMSMN1; SMN2NPC1 | |
| SCHEMBL2554145 | 0.66 | ALDH1A1 (0.56) | CSNK2A2CSNK2BCSNK2A1CSNK2A3TSHR | |
| SCHEMBL3340692 | 0.65 | TSHR (0.49) | LDHALDHBTSHRSRD5A2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122184-A1 | Cyanomethyl derivatives as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122184-A1 | Cyanomethyl derivatives as cysteine protease inhibitors | CTSF, CTSB, CTSK | LDHA 3136/4885LDHB 1159/4885CSNK2A2 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.