Methylglyoxal

Methylglyoxal

SCHEMBL950599

CC(=O)C=O.COC(C)OC

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL593191 0.82 LMNA (0.43) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL9684849 0.81 ALDH1A1 (0.32) ALDH1A1TSHR
Acetic Acid SCHEMBL10711426 0.79 FFAR3 (0.47) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
Acetamide SCHEMBL11118916 0.77 LMNA (0.50) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
Acetaldehyde SCHEMBL225414 0.76
Bicarbonate SCHEMBL6258274 0.76 TP53 (0.39) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL3207667 0.76 ALDH1A1 (0.36) ALDH1A1
Acetaldehyde SCHEMBL1401397 0.76 TSHR (0.43) TSHR
SCHEMBL23120199 0.75 CHRNB2 (0.33)
SCHEMBL8622405 0.75 ALDH1A1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10314787-B2 Controlled release delivery device comprising an organosol coat INTELLIPHARMACEUTICS CORPORATION (CA) 2019-06-11 US claimed
US-20190076363-A1 CONTROLLED RELEASE DELIVERY DEVICE COMPRISING AN ORGANOSOL COAT INTELLIPHARMACEUTICS CORPORATION (CA) 2019-03-14 US claimed
US-10159649-B2 Controlled release delivery device comprising an organosol coat INTELLIPHARMACEUTICS CORPORATION (CA) 2018-12-25 US claimed
US-9561188-B2 Controlled release delivery device comprising an organosol coat INTELLIPHARMACEUTICS CORPORATION (CA) 2017-02-07 US claimed
EP-2007360-B1 CONTROLLED RELEASE DELIVERY DEVICE COMPRISING AN ORGANOSOL COAT ODIDI ISA (CA) 2014-11-26 EP claimed
CN-103274962-A N-[4-(1-(2-propinyl)-3, 4-dioxo-n-butyl) benzoyl]-L-glutamic dialkyl ester and preparation method thereof SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD 2013-09-04 CN claimed
US-7638658-B2 Ethynylation process DSM IP ASSETS B.V. (NL) 2009-12-29 US claimed
US-20090220613-A1 CONTROLLED RELEASE DELIVERY DEVICE COMPRISING AN ORGANOSOL COAT 1001112561 ONTARIO INC. (CA) 2009-09-03 US claimed
EP-2007360-A1 CONTROLLED RELEASE DELIVERY DEVICE COMPRISING AN ORGANOSOL COAT Odidi, Isa (CA) 2008-12-31 EP claimed
EP-1532092-B1 ETHINYLATION PROCESS DSM IP ASSETS BV (NL) 2008-11-05 EP claimed
EP-1532092-A1 ETHYNYLATION PROCESS DSM IP Assets B.V. (NL) 2005-05-25 EP claimed
WO-2004018400-A1 ETHYNYLATION PROCESS DSM IP ASSETS B.V. (NL) 2004-03-04 WO claimed
US-6398938-B2 WHERE THE ANODICALLY POLARIZED LAYER ON THE ANODE SUPPORT IS FORMED IN SITU BY PRECOATING; EXCLUDES THE OXIDATION OF PHOSPHONOMETHYLIMINODIACETIC ACID; HIGH YIELDS BASF AKTIENGESELLSCHAFT (DE) 2002-06-04 US claimed
US-20010019020-A1 Process for electrochemical oxidation of organic compounds BASF AKTIENGESELLSCHAFT (DE) 2001-09-06 US claimed
EP-0782983-A2 Process of preparing 2,2'-(1-Methyl-1,2-Ethanediylidene) bis (Hydrazine carboximidamide) SANOFI (FR) 1997-07-09 EP claimed
US-5610016-A REACTING A GLYOXAL DERIVATIVE, CHEMILUMINESCENCE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-03-11 US claimed
EP-0718693-A2 Photoresist compositions and components SHIPLEY COMPANY INC. (US) 1996-06-26 EP claimed
EP-0675360-A2 Method for measuring adenyl group containing substances using heteropoly acid MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-10-04 EP claimed
EP-0273026-A2 Solvents for Photoresist compositions SHIPLEY COMPANY INC. (US) 1988-06-29 EP claimed
US-4361702-A FROM PYRUVALDEHYDE ACETAL AND ACETONITRILE ALBERTA RESEARCH COUNCIL (CA) 1982-11-30 US claimed