SCHEMBL594656

SCHEMBL594656

C=CCCCCCCCCC(=CCCCC)CCCCCCC=C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
ALDH1A1 P00352 3/20 0.56
MAPT P10636 3/20 0.45
ABCC4 O15439 1/20 0.45
LMNA P02545 2/20 0.44
F7 P08709 2/20 0.41
F3 P13726 2/20 0.41
EP300 Q09472 1/20 0.38
FAAH O00519 2/20 0.38
TERT O14746 3/20 0.37
BLM P54132 2/20 0.37
HSD17B10 Q99714 2/20 0.37
FABP4 P15090 2/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37
APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17262057 0.98 TSHR (0.56) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL29284391 0.96 TSHR (0.54) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL6556651 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL1274968 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL5716967 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL3737327 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL7625618 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL11670742 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL6698175 0.96 TSHR (0.64) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL29284451 0.96 TSHR (0.56) TSHRALDH1A1MAPTABCC4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198500-B2 Process to make base oil from Fischer-Tropsch condensate by concurrent oligomerization and alkylation CHEVRON U.S.A. INC. (US) 2012-06-12 US disclosed
US-20120053380-A1 PROCESS TO MAKE BASE OIL FROM FISCHER-TROPSCH CONDENSATE BY CONCURRENT OLIGOMERIZATION AND ALKYLATION CHEVRON U.S.A. INC. (US) 2012-03-01 US disclosed
US-8119851-B2 Process to make base oil from fischer-tropsch condensate CHEVRON U.S.A. INC. (US) 2012-02-21 US disclosed
US-8115040-B2 Prepared by oligomerization of a mixture comprising olefins and isoparaffins to produce an alkylated (\"capped\") olefin oligomer having a very high VI and a low cloud point; process preferably uses an acidic chloroaluminate ionic liquid catalyst system CHEVRON U.S.A. INC. (US) 2012-02-14 US disclosed
US-7973204-B2 oligomerizing an olefin feed produced by thermal cracking of a waxy feed in an ionic liquid chloroaluminate catalyst oligomerization zone, alkylating with an isoparaffin such as isobutane to make lubricating base oil; oils containing branched paraffins and low olefin concentrations CHEVRON U.S.A. INC. (US) 2011-07-05 US disclosed
US-7973205-B2 Process to make a lubricant component by oligomerizing and alkylating at a molar ratio of olefin to isoparaffin of at least 0.8 CHEVRON U.S.A. INC. (US) 2011-07-05 US disclosed
US-20110004038-A1 PROCESS TO MAKE BASE OIL FROM THERMALLY CRACKED WAXY FEED USING IONIC LIQUID CATALYST CHEVRON U.S.A., INC. 2011-01-06 US disclosed
US-20100204531-A1 PROCESS TO MAKE A LUBRICANT COMPONENT BY OLIGOMERIZING AND ALKYLATING AT A MOLAR RATIO OF OLEFIN TO ISOPARAFFIN OF AT LEAST 0.8 CHEVRON U.S.A. INC. 2010-08-12 US disclosed
US-7732654-B2 Oligomerizing and alkylating with an ionic liquid at a molar ratio of olefin to isoparaffin of at least 0.8 CHEVRON U.S.A. INC. (US) 2010-06-08 US disclosed
US-7723556-B2 Process to make base oil from thermally cracked waxy feed using ionic liquid catalyst CHEVRON U.S.A. INC. (US) 2010-05-25 US disclosed
US-20070142684-A1 Alkylation of oligomers to make superior lubricant or fuel blendstock CHEVRON U.S.A. INC. 2007-06-21 US disclosed
US-20070142685-A1 Process for making and composition of superior lubricant or lubricant blendstock CHEVRON U.S.A. INC. 2007-06-21 US disclosed
US-20070142691-A1 Process for the formation of a superior lubricant or fuel blendstock by ionic liquid oligomerization of olefins in the presence of isoparaffins CHEVRON U.S.A. INC. 2007-06-21 US disclosed
EP-0769546-B1 Antiwear enhancing composition for lubricants and functional fluids LUBRIZOL CORP (US) 2003-07-30 EP disclosed
US-5759965-A OVERBASED COMPOUND; AUTOMATIC TRANSMISSION FLUID THE LUBRIZOL CORPORATION (US) 1998-06-02 US disclosed
EP-0769546-A2 Antiwear enhancing composition for lubricants and functional fluids The Lubrizol Corporation (US) 1997-04-23 EP disclosed
US-5484542-A OIL ADDITIVES THE LUBRIZOL CORPORATION (US) 1996-01-16 US disclosed
EP-0586258-A2 Sulfurized overbased compositions The Lubrizol Corporation (US) 1994-03-09 EP disclosed
US-4446039-A Organic compositions containing hydroxy-aromatic compounds useful as additives for fuels and lubricants THE LUBRIZOL CORPORATION (US) 1984-05-01 US disclosed
US-4147643-A REACTION PRODUCT OF PHENOL, FORMALDEHYDE, AND A CHLORO-PHENOL MODIFIED POLYOLEFIN THE LUBRIZOL CORPORATION (US) 1979-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142684-A1 Alkylation of oligomers to make superior lubricant or fuel blendstock PUF60, INTS9, INTS6 TSHR 4846/4885ALDH1A1 2933/4885MAPT 1230/4885
US-20100204531-A1 PROCESS TO MAKE A LUBRICANT COMPONENT BY OLIGOMERIZING AND ALKYLATING AT A MOLAR RATIO OF OLEFIN TO ISOPARAFFIN OF AT LEAST 0.8 IGLV6-57, MACF1, ATXN10 TSHR 4082/4885ALDH1A1 4100/4885MAPT 1656/4885
US-20120053380-A1 PROCESS TO MAKE BASE OIL FROM FISCHER-TROPSCH CONDENSATE BY CONCURRENT OLIGOMERIZATION AND ALKYLATION BPTF, RTF1, MACF1 TSHR 4042/4885ALDH1A1 2880/4885MAPT 1842/4885
US-20070142691-A1 Process for the formation of a superior lubricant or fuel blendstock by ionic liquid oligomerization of olefins in the presence of isoparaffins CEL, BRPF1, INTS9 TSHR 4845/4885ALDH1A1 2693/4885MAPT 1982/4885
US-20070142685-A1 Process for making and composition of superior lubricant or lubricant blendstock PRPF6, INTS6, ANXA6 TSHR 4864/4885ALDH1A1 3797/4885MAPT 857/4885
US-20110004038-A1 PROCESS TO MAKE BASE OIL FROM THERMALLY CRACKED WAXY FEED USING IONIC LIQUID CATALYST SHARPIN, NCLN, YIF1A TSHR 4597/4885ALDH1A1 4435/4885MAPT 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.