Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906810 | 0.95 | HTR2A (0.38) | HTR2ACALM1HTR2CHTR2BBCL2 | |
| SCHEMBL5677912 | 0.83 | BCL2L1 (0.46) | HTR2ACALM1HTR2CHTR2BBCL2L1 | |
| SCHEMBL11947277 | 0.79 | HTR2C (0.48) | HTR2AHTR2CHTR2BHRH1 | |
| SCHEMBL8151881 | 0.78 | PNMT (0.64) | HTR2ACALM1HTR2BBCL2BCL2L1 | |
| SCHEMBL8917078 | 0.74 | DRD2 (0.46) | HTR2ACALM1HTR2BBCL2BCL2L1 | |
| SCHEMBL30882161 | 0.74 | KDM4E (0.41) | HTR2AHTR2CHTR2BPNMTCYP1A2 | |
| SCHEMBL7176180 | 0.74 | CYP11B1 (0.41) | HTR2ACALM1HTR2CHTR2BBCL2 | |
| SCHEMBL11631564 | 0.73 | ALDH1A1 (0.47) | HTR2ACALM1HTR2CHTR2BCYP1A2 | |
| SCHEMBL23527423 | 0.73 | MAOA (0.52) | PNMTCYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL1724852 | 0.72 | TRPV1 (0.53) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |