Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948774 | 0.84 | TAAR1 (0.65) | SLC2A1TAAR1HDAC1HDAC6CHRM2 | |
| SCHEMBL2951800 | 0.80 | CALM1 (0.59) | CHRM2 | |
| SCHEMBL4304462 | 0.77 | MTNR1A (0.70) | SIGMAR1TAAR1HDAC1HDAC6CHRM2 | |
| SCHEMBL2958349 | 0.76 | SLC6A4 (0.58) | SIGMAR1KMT2AADRB2 | |
| Hydrochloric Acid SCHEMBL10582570 | 0.74 | SLC6A4 (0.56) | SIGMAR1KMT2AADRB2 | |
| SCHEMBL5954572 | 0.72 | TAAR1 (0.43) | SLC2A1KMT2ATAAR1HDAC1HDAC6 | |
| SCHEMBL14655805 | 0.72 | TAAR1 (0.67) | SIGMAR1SLC2A1TAAR1CHRM2ADRB2 | |
| SCHEMBL4949653 | 0.71 | TAAR1 (0.67) | SIGMAR1TAAR1CHRM2 | |
| SCHEMBL8783348 | 0.71 | FFAR1 (0.54) | — | |
| SCHEMBL4031646 | 0.71 | ADRB2 (0.62) | SIGMAR1SLC2A1TAAR1CHRM2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692096-A1 | HYDROXYLAMINE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-23 | — | — | EP | claimed |
| WO-2005058800-A1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-30 | — | — | WO | claimed |