Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954569 | 0.72 | SIGMAR1 (0.54) | TAAR1CHRM2SLC2A1MTNR1AMTNR1B | |
| SCHEMBL4304462 | 0.70 | MTNR1A (0.70) | TAAR1CHRM2MTNR1AMTNR1BCHRM1 | |
| SCHEMBL2948774 | 0.69 | TAAR1 (0.65) | TAAR1CHRM2ALDH1A1SLC2A1ADRB2 | |
| SCHEMBL17788984 | 0.69 | TAAR1 (0.65) | TAAR1CHRM2ADRB2CHRM1CHRM3 | |
| SCHEMBL9856490 | 0.67 | CHRM2 (0.56) | TAAR1CHRM2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7450409 | 0.66 | TAAR1 (0.70) | TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL27499005 | 0.66 | TAAR1 (0.56) | TAAR1ALDH1A1MTNR1AMTNR1BHTT | |
| SCHEMBL10662936 | 0.66 | MTNR1A (0.53) | TAAR1ALDH1A1MTNR1AMTNR1BADRB2 | |
| SCHEMBL6224557 | 0.65 | TAAR1 (0.73) | TAAR1CHRM2ADRB2CHRM1CHRM3 | |
| SCHEMBL4734640 | 0.65 | TAAR1 (0.54) | TAAR1CHRM2ALDH1A1SCN8AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692096-A1 | HYDROXYLAMINE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-23 | — | — | EP | claimed |
| WO-2005058800-A1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-30 | — | — | WO | claimed |