SCHEMBL595458

SCHEMBL595458

CCC12CC3CC(CC(C3)C1C=C(C)C(=O)O)C2

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CD81 P60033 1/20 0.32
THRB P10828 1/20 0.31
CYP2C9 P11712 1/20 0.31
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207202 0.88 CD81 (0.32) CD81THRBCYP2C9
SCHEMBL7521808 0.80
SCHEMBL1089320 0.80 THRB (0.33) CD81THRBCYP2C9
SCHEMBL596454 0.80 CD81 (0.34) CD81THRBCYP2C9
SCHEMBL6559871 0.77 THRB (0.32) CD81THRBCYP2C9
Methacrylic Acid SCHEMBL28235913 0.71 HSD11B1 (0.33) KMT2ASMN1; SMN2
SCHEMBL1937747 0.70 GRIN2D (0.32)
SCHEMBL31160481 0.70 KMT2A (0.35) KMT2ASMN1; SMN2
SCHEMBL7523676 0.69 KMT2A (0.32) KMT2ASMN1; SMN2
SCHEMBL244479 0.68 HSD11B1 (0.38) THRBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557501-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-15 US claimed
US-20120178029-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS ESPECIALLY SUITABLE FOR ION IMPLANT APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-12 US claimed
US-8182978-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-05-22 US claimed
US-8557501-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-15 US disclosed
US-20120178029-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS ESPECIALLY SUITABLE FOR ION IMPLANT APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-12 US disclosed
US-8182978-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-05-22 US disclosed
US-8115036-B2 Fluorine-containing cyclic compound, fluorine-containing polymer compound, resist material using same and method for forming pattern CENTRAL GLASS COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-20100204422-A1 Fluorine-Containing Cyclic Compound, Fluorine-Containing Polymer Compound, Resist Material Using Same and Method for Forming Pattern CENTRAL GLASS COMPANY, LIMITED (JP) 2010-08-12 US disclosed
US-20100196825-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS ESPECIALLY SUITABLE FOR ION IMPLANT APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-08-05 US disclosed
WO-2010086288-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS ESPECIALLY SUITABLE FOR ION IMPLANT APPLICATIONS AND METHOD OF FORMING A PATTERN USING IT INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-08-05 WO disclosed
US-7736835-B2 Fluorine-containing cyclic compound, fluorine-containing polymer compound, resist material using same and method for forming pattern CENTRAL GLASS COMPANY, LIMITED (JP) 2010-06-15 US disclosed
WO-2009019574-A1 PHOTORESIST COMPOSITION FOR DEEP UV AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-02-12 WO disclosed
US-20090042148-A1 Photoresist Composition for Deep UV and Process Thereof AZ ELECTRONIC MATERIALS USA CORP. 2009-02-12 US disclosed
US-20080003517-A1 Fluorine-Containing Cyclic Compound, Fluorine-Containing Polymer Compound, Resist Material Using Same and Method for Forming Pattern CENTRAL GLASS COMPANY, LIMITED (JP) 2008-01-03 US disclosed
WO-2002021212-A2 FLUORINATED PHENOLIC POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING SAME SHIPLEY COMPANY, L.L.C. (US) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204422-A1 Fluorine-Containing Cyclic Compound, Fluorine-Containing Polymer Compound, Resist Material Using Same and Method for Forming Pattern AFF1, AFF2, FGFR1 CD81 2138/4885THRB 3200/4885CYP2C9 1871/4885
US-20080003517-A1 Fluorine-Containing Cyclic Compound, Fluorine-Containing Polymer Compound, Resist Material Using Same and Method for Forming Pattern AFF1, AFF2, FGFR1 CD81 2138/4885THRB 3200/4885CYP2C9 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.