Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRF1 | P14222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956440 | 0.87 | WNT3A (0.43) | WNT3AADORA2AADORA1MAPT | |
| SCHEMBL5956384 | 0.84 | SCN10A (0.47) | WNT3APPARDADORA3 | |
| SCHEMBL5956662 | 0.82 | LOXL2 (0.55) | LOXL2IRAK4WNT3ATGFBR1 | |
| SCHEMBL5956490 | 0.82 | WNT3A (0.39) | LOXL2IRAK4WNT3AP2RX7TGFBR1 | |
| SCHEMBL5956629 | 0.81 | TGFBR1 (0.47) | LOXL2WNT3AP2RX7TGFBR1MEN1 | |
| SCHEMBL5956502 | 0.81 | PRKAB2 (0.47) | TGFBR1 | |
| SCHEMBL5956453 | 0.80 | TGFBR1 (0.45) | LOXL2WNT3ATGFBR1 | |
| SCHEMBL5956595 | 0.80 | ACACA (0.43) | ACACATGFBR1TSHRMEN1KMT2A | |
| SCHEMBL5956509 | 0.79 | IRAK4 (0.41) | LOXL2IRAK4WNT3AP2RX7TGFBR1 | |
| SCHEMBL5790926 | 0.76 | HDAC1 (0.46) | WNT3AADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | ACACA 1480/4885LOXL2 758/4885IRAK4 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.