Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231313 | 0.84 | RAB9A (0.46) | — | |
| SCHEMBL5907457 | 0.83 | KDM1A (0.38) | KDM1AHDAC1ABL1BCRIRAK4 | |
| SCHEMBL5956373 | 0.82 | WNK1 (0.45) | HDAC1ABL1BCRPARP1 | |
| SCHEMBL5956396 | 0.81 | CYP1A2 (0.39) | ABL1BCR | |
| SCHEMBL5907501 | 0.79 | HDAC1 (0.47) | KDM1AHDAC1ACVR1CHUKMAPK8 | |
| SCHEMBL5956595 | 0.79 | ACACA (0.43) | KDM1AHDAC1ABL1BCR | |
| SCHEMBL5956574 | 0.79 | SCN10A (0.54) | ABL1BCR | |
| SCHEMBL5907471 | 0.78 | ABL1 (0.51) | ABL1BCR | |
| SCHEMBL5907452 | 0.78 | HDAC1 (0.50) | KDM1AHDAC1ACVR1MAPK8ROCK2 | |
| SCHEMBL5956425 | 0.77 | HPGD (0.52) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054791-A1 | low density, high impact strength, high tear resistance and high clarity, a degree of stiffness usually found in products made from resin of significantly higher density | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-03-10 | — | — | US | claimed |
| EP-1461364-A1 | ETHYLENE/ALPHA-OLEFIN COPOLYMER MADE WITH A NON-SINGLE-SITE/SINGLE-SITE CATALYST COMBINATION, ITS PREPARATION AND USE | Exxonmobil Chemical Patents Inc. (US) | 2004-09-29 | — | — | EP | claimed |
| WO-2003048213-A1 | ETHYLENE/ALPHA-OLEFIN COPOLYMER MADE WITH A NON-SINGLE-SITE/SINGLE-SITE CATALYST COMBINATION, ITS PREPARATION AND USE | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2003-06-12 | — | — | WO | claimed |
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | DODIC NERINA | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | SMAD2, SMAD3, ALK | EGFR 208/4885KDM1A 1516/4885HDAC1 1275/4885 |
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | EGFR 56/4885KDM1A 2586/4885HDAC1 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.